Department of Medicine, Albert Einstein College of Medicine, 111 East 210th Street, Rosenthal 2C, Bronx, NY 10467, USA.
Department of Medicine, Albert Einstein College of Medicine, 111 East 210th Street, Rosenthal 2C, Bronx, NY 10467, USA.
Clin Liver Dis. 2016 May;20(2):387-401. doi: 10.1016/j.cld.2015.10.004. Epub 2016 Feb 18.
Nonalcoholic fatty liver disease (NAFLD) is an important cause of liver disease that is often associated with the metabolic syndrome. There is a growing awareness that extrahepatic complications occur in individuals with NAFLD, especially an increased risk of cardiovascular disease. Development of diabetes mellitus, chronic kidney disease, colorectal cancer, and endocrinopathies has been linked to NAFLD. This article reviews the extrahepatic complications affecting individuals with NAFLD and the pathogenesis underlying their development.
非酒精性脂肪性肝病（NAFLD）是一种重要的肝病病因，常与代谢综合征相关。人们越来越意识到，NAFLD 患者会发生肝外并发症，尤其是心血管疾病风险增加。糖尿病、慢性肾脏病、结直肠癌和内分泌疾病的发生与 NAFLD 相关。本文综述了影响 NAFLD 患者的肝外并发症及其发病机制。
