Roach J A, Sphon J A, Easterling J A, Calvey E M
Center for Food Safety and Applied Nutrition, Food and Drug Administration, Washington, DC 20204.
Biomed Environ Mass Spectrom. 1989 Jan;18(1):64-70. doi: 10.1002/bms.1200180109.
A capillary supercritical fluid chromatography/mass spectrometry interface incorporating a heated frit restrictor is described. The trichothecene mycotoxins T-2 toxin, deoxynivalenol and roridin A were used to evaluate the effect of restrictor temperature and carbon dioxide mobile phase on the negative ion chemical ionization (CI) spectra of these compounds under electron capture, proton abstraction and chloride attachment conditions. Restrictor temperatures less than 100 degrees C above the melting point of the samples retarded sample transfer into the mass spectrometer, but neither restrictor temperature nor carbon dioxide mobile phase significantly affected negative ion CI conditions.
描述了一种带有加热烧结限流器的毛细管超临界流体色谱/质谱联用接口。使用单端孢霉烯族霉菌毒素T-2毒素、脱氧雪腐镰刀菌烯醇和棒曲霉素A来评估限流器温度和二氧化碳流动相对这些化合物在电子捕获、质子提取和氯附着条件下的负离子化学电离（CI）光谱的影响。限流器温度低于样品熔点100摄氏度以上会阻碍样品转移到质谱仪中，但限流器温度和二氧化碳流动相均未对负离子CI条件产生显著影响。
