Kaiser Permanente Riverside, Riverside, CA, USA.
Retina Consultants San Diego, Poway, CA, USA.
Ophthalmol Ther. 2016 Jun;5(1):21-30. doi: 10.1007/s40123-016-0047-5. Epub 2016 Apr 11.
Advanced or end-stage age-related macular degeneration (AMD) results in significant visual impairment and a substantially reduced quality of life for patients. Therapeutic options for people with bilateral moderate or profound vision loss caused by end-stage AMD are limited. Although medical treatment capable of reversing the functional vision loss that results from end-stage AMD is non-existent, there are now treatments that can reverse some of that functional vision loss, including the implantable miniature telescope (IMT). This review article discusses the science behind the IMT, evaluates the data from clinical studies, and weighs the pros and cons of the technology.
晚期或终末期年龄相关性黄斑变性(AMD)会导致患者视力严重受损,生活质量大幅下降。对于因终末期 AMD 导致双眼中度或重度视力丧失的患者,治疗选择有限。虽然目前还没有能够逆转终末期 AMD 导致的功能性视力丧失的治疗方法,但现在有一些治疗方法可以逆转部分这种功能性视力丧失,包括可植入微型望远镜(IMT)。本文综述了 IMT 的相关科学原理,评估了临床研究数据,并权衡了该技术的优缺点。