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腰椎硬膜内毛细血管瘤病例报告

Case report of lumbar intradural capillary hemangioma.

作者信息

Unnithan Ajaya Kumar Ayyappan, Joseph T P, Gautam Amol, Shymole V

机构信息

Mar Gregorios Memorial Muthoot Medical Centre, Kozhencherry, Kerala, India.

出版信息

Surg Neurol Int. 2016 Mar 2;7(Suppl 5):S139-41. doi: 10.4103/2152-7806.177886. eCollection 2016.

DOI:10.4103/2152-7806.177886
PMID:27069745
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4802984/
Abstract

BACKGROUND

Capillary hemangioma is a rare tumor in spinal intradural location. Despite the rarity, early recognition is important because of the risk of hemorrhage. This is a case report of a woman who had capillary hemangioma of cauda equina.

CASE DESCRIPTION

A 54 -year-old woman presented with a low backache, radiating to the left leg for 2 months. She had left extensor hallucis weakness, sensory impairment in left L5 dermatome, and mild tenderness in lower lumbar spine. Magnetic resonance imaging (MRI) LS spine showed L4/5 intradural tumor, completely occluding canal in myelogram, enhancing with contrast, s/o benign nerve sheath tumor. L4 laminectomy was done. Reddish tumor was seen originating from a single root. It was removed preserving the root. Postoperatively, she was relieved of symptoms. MRI showed no residue. Histopathology showed lobular proliferation of capillary-sized blood vessels and elongated spindle cells. Immunohistochemistry showed CD34 positivity in endothelial cell lining of blood vessel and smooth muscle actin positivity in blood vessel muscle cells. HPR-capillary hemangioma.

CONCLUSION

Although rare, capillary hemangioma should be in the differential diagnosis of intradural tumors. It closely mimics nerve sheath tumor.

摘要

背景

毛细血管瘤是一种罕见的脊髓硬膜内肿瘤。尽管罕见,但由于存在出血风险,早期识别很重要。本文报告一例马尾毛细血管瘤女性患者。

病例描述

一名54岁女性,腰痛伴向左下肢放射痛2个月。左足背伸肌无力,左侧L5皮节感觉障碍,下腰椎轻度压痛。腰椎磁共振成像(MRI)显示L4/5硬膜内肿瘤,脊髓造影显示肿瘤完全阻塞椎管,增强扫描有强化,考虑为良性神经鞘瘤。行L4椎板切除术。可见一红色肿瘤起源于单一神经根。保留神经根将肿瘤切除。术后患者症状缓解。MRI显示无残留。组织病理学显示毛细血管大小的血管呈小叶状增生,有细长的梭形细胞。免疫组化显示血管内皮细胞衬里CD34阳性,血管肌细胞平滑肌肌动蛋白阳性。病理诊断为毛细血管瘤。

结论

尽管罕见,但毛细血管瘤应列入硬膜内肿瘤的鉴别诊断。它与神经鞘瘤极为相似。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1392/4802984/376862802349/SNI-7-139-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1392/4802984/b7eb735340bc/SNI-7-139-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1392/4802984/150daf23600d/SNI-7-139-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1392/4802984/962310189096/SNI-7-139-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1392/4802984/c72340151ee1/SNI-7-139-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1392/4802984/12b76cc70698/SNI-7-139-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1392/4802984/376862802349/SNI-7-139-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1392/4802984/b7eb735340bc/SNI-7-139-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1392/4802984/150daf23600d/SNI-7-139-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1392/4802984/962310189096/SNI-7-139-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1392/4802984/c72340151ee1/SNI-7-139-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1392/4802984/12b76cc70698/SNI-7-139-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1392/4802984/376862802349/SNI-7-139-g006.jpg

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本文引用的文献

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Cases J. 2009 Jan 22;2(1):80. doi: 10.1186/1757-1626-2-80.
3
Spinal intradural extramedullary capillary hemangioma: MR imaging findings.脊髓硬膜内髓外毛细血管瘤:磁共振成像表现
Intradural extramedullary capillary hemangioma of the cauda equina: case report of a rare spinal tumor.
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AJNR Am J Neuroradiol. 2001 Apr;22(4):799-802.
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Capillary hemangioma in the cauda equina: neuroradiological findings.马尾神经的毛细血管瘤:神经放射学表现
Neuroradiology. 1991;33(5):458-61. doi: 10.1007/BF00598628.