Connor Nicholas E, Islam Mohammad Shahidul, Arvay Melissa L, Baqui Abdullah H, Zaidi Anita K, Soofi Sajid B, Panigrahi Pinaki, Bose Anuradha, Islam Maksuda, El Arifeen Shams, Saha Samir K, Qazi Shamim A
From the *Centre for Child and Adolescent Health, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh; †Child Health Research Foundation, Dhaka, Bangladesh; ‡Centers for Disease Control and Prevention, Atlanta, Georgia; §Department of International Health, International Center for Maternal and Newborn Health, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland; ¶The Aga Khan University, Karachi, Pakistan; ‖Center for Global Health and Development, College of Public Health, University of Nebraska Medical Center, Omaha, Nebraska; **Christian Medical College, Vellore, India; and ††Department of Maternal, Newborn, Child and Adolescent Health, World Health Organization, Geneva, Switzerland.
Pediatr Infect Dis J. 2016 May;35(5 Suppl 1):S39-44. doi: 10.1097/INF.0000000000001105.
The Aetiology of Neonatal Infection in South Asia (ANISA) study maintains operations in Bangladesh, India and Pakistan. We developed and deployed a multilayered monitoring system to measure performance indicators of field sites and laboratory operations. This system allows for real-time provision of feedback to study site teams and project stakeholders. The goal of this monitoring and evaluation system is to promote optimal performance and consistency in protocol application at all sites over the course of the study, thereby safeguarding the validity of project findings. This article describes each of the interdependent monitoring layers that were conceptualized, developed and employed by the ANISA coordination team.
Layers of monitoring include site-level, central and database-related activities along with periodic site visitation. We provide a number of real-world examples of how feedback from the ANISA monitoring system directly informs a number of crucial decisions and course corrections during the project.
The ANISA monitoring system represents a transparent, understandable and practical resource for development of project monitoring systems in complex multisite health research projects.
南亚新生儿感染病因研究（ANISA）在孟加拉国、印度和巴基斯坦开展研究工作。我们开发并部署了一个多层监测系统，以衡量实地站点和实验室操作的绩效指标。该系统能够实时向研究站点团队和项目利益相关者提供反馈。此监测与评估系统的目标是在研究过程中促进所有站点在方案应用方面的最佳绩效和一致性，从而保障项目研究结果的有效性。本文介绍了ANISA协调团队构思、开发和使用的相互依存的各监测层面。
监测层面包括站点层面、中心层面和与数据库相关的活动以及定期的站点访问。我们提供了一些实际案例，说明ANISA监测系统的反馈如何在项目期间直接为一些关键决策和流程调整提供依据。
ANISA监测系统是复杂多站点健康研究项目中开发项目监测系统的一种透明、易懂且实用的资源。
