Jovanović Milan, Janjusević Natasa, Mirković Darko, Vulović Maja, Milev Bosko, Mitrović Miroslav, Trifunović Bratislav
Vojnosanit Pregl. 2016 Feb;73(2):205-7. doi: 10.2298/vsp150126021j.
Primary extragonadal seminomas are rare tumors. There have been only a few cases of the primary retroperitoneal seminomas reported in the literature up to date.
We reported a 56-year-old man with giant primary retroperitoneal seminoma presented with the enlargement of the left side of the abdomen and deep venous thrombosis of the left leg. Computed tomography of the abdomen showed a large tumor occupying the left part of the retroperitoneal space with 23 x 13 cm in diameter. Firm tumor mass having 25 x 15 cm in diameter was surgically removed from the left retroperitoneum. The tumor adhered the tunica adventitia of the aorta and it was carefully resected from the aortic wall. The diagnosis of seminoma was made during histopathological examination. The patient underwent chemotherapy. Two years after finished chemotherapy the patient accepted left orchiectomy with the aim of eliminating the possibility of the occult malignancy of the testicle. Histopathological analysis of the testicular tissue was normal and the diagnosis of primary retroperitoneal seminoma was confirmed. CONCLUSION. Despite its small incidence in general population, the diagnosis of retroperitoneal seminoma should be considered in male patients with nonspecific symptoms and with retroperitoneal tumor mass.
原发性性腺外精原细胞瘤是罕见肿瘤。迄今为止，文献中仅报道了少数原发性腹膜后精原细胞瘤病例。
我们报告了一名56岁男性，患有巨大原发性腹膜后精原细胞瘤，表现为腹部左侧肿大及左腿深静脉血栓形成。腹部计算机断层扫描显示一个巨大肿瘤占据腹膜后间隙左侧，直径达23×13厘米。从左腹膜后手术切除了直径为25×15厘米的坚实肿瘤块。肿瘤附着于主动脉外膜，遂小心地从主动脉壁上切除。在组织病理学检查中确诊为精原细胞瘤。患者接受了化疗。化疗结束两年后，患者接受了左侧睾丸切除术，目的是消除睾丸隐匿性恶性肿瘤的可能性。睾丸组织的组织病理学分析正常，原发性腹膜后精原细胞瘤的诊断得到证实。结论：尽管腹膜后精原细胞瘤在普通人群中的发病率较低，但对于有非特异性症状且有腹膜后肿瘤块的男性患者，应考虑诊断为腹膜后精原细胞瘤。
