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后循环脑血管病综合征:诊断与管理。

Posterior circulation cerebrovascular syndromes: diagnosis and management.

机构信息

Stroke Prevention Research Unit, Nuffield Department of Clinical Neurosciences, Oxford, UK.

Department of Neurology, University Hospital (Inselspital) and University of Bern, Bern, Switzerland.

出版信息

J Neurol Neurosurg Psychiatry. 2017 Jan;88(1):45-53. doi: 10.1136/jnnp-2015-311299. Epub 2016 Apr 12.

Abstract

One in five strokes affects the posterior circulation. Diagnosing posterior circulation stroke can be challenging, as the vascular anatomy can be variable, and because presenting symptoms are often non-specific and fluctuating. Nevertheless, making the correct diagnosis is important, as these strokes have a high chance of recurrence, can be life threatening, and can lead to equally life-threatening complications. Investigation and management largely follow those for stroke in general, although some specific differences exist. These include the preferred use of MRI for diagnosing posterior fossa lesions, the management of basilar artery thrombosis, which may have a longer time window for recanalisation therapy, and the use of endovascular therapies for secondary prevention, which, so far, have not shown any benefit in the treatment of vertebral or basilar artery stenosis. In this review, we summarise the anatomy, aetiology and presentation of posterior circulation stroke, and discuss current approaches to management.

摘要

五分之一的中风影响后循环。诊断后循环中风具有挑战性,因为血管解剖结构可能存在差异,而且由于症状通常是非特异性和波动的。然而,做出正确的诊断很重要,因为这些中风复发的可能性很高,可能危及生命,并可能导致同样危及生命的并发症。调查和管理在很大程度上遵循一般中风的方法,尽管存在一些特定的差异。这些差异包括首选 MRI 用于诊断后颅窝病变,基底动脉血栓形成的管理,其可能具有更长的再通治疗时间窗,以及血管内治疗用于二级预防,迄今为止,在后循环狭窄的治疗中,这些治疗并没有显示出任何益处。在这篇综述中,我们总结了后循环中风的解剖、病因和表现,并讨论了当前的治疗方法。

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