Ross Lynda J, Wallin Siobhan, Osland Emma J, Memon Muhammed Ashraf
Department of Nutrition and Dietetics, Royal Brisbane & Women's Hospital, Brisbane, QLD, Australia.
Menzies Health Institute Queensland, Griffith University, Gold Coast campus, Southport, QLD, Australia.
Obes Surg. 2016 Jun;26(6):1343-51. doi: 10.1007/s11695-016-2167-3.
This systematic review assessed feasibility and effectiveness of preoperative meal replacements to improve surgical outcomes for obese patients.
PRISMA guidelines were followed and electronic databases searched for articles between January 1990 and March 2015.
Fifteen studies (942 participants including 351 controls) were included, 13 studies (n = 750) in bariatric patients. Adverse effects and dropout rates were minimal. Ten out of 14 studies achieved 5-10 % total weight loss. Six of six studies reporting liver volume achieved 10 % reduction. Endpoints for perioperative risks and outcomes were too varied to support definitive risk benefit.
Commercial meal replacements are feasible, have minimal side effects and facilitate weight loss and liver shrinkage in free-living obese patients awaiting elective surgery. A reduction in surgical risk is unclear.
本系统评价评估了术前代餐对改善肥胖患者手术结局的可行性和有效性。
遵循PRISMA指南，检索1990年1月至2015年3月期间的电子数据库中的文章。
纳入了15项研究（942名参与者，包括351名对照），其中13项研究（n = 750）涉及肥胖症患者。不良反应和脱落率极低。14项研究中有10项实现了5%至10%的总体体重减轻。报告肝脏体积的6项研究中有6项实现了10%的缩小。围手术期风险和结局的终点差异太大，无法支持明确的风险效益评估。
商业代餐是可行的，副作用极小，有助于等待择期手术的肥胖患者减轻体重和肝脏缩小。手术风险的降低尚不清楚。
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