Grau Lauretta E, Zhan Weihai, Heimer Robert
Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, USA.
Department of Children and Families, Hartford, USA.
Drug Alcohol Rev. 2016 Sep;35(5):628-36. doi: 10.1111/dar.12396. Epub 2016 Apr 13.
Little is known about injection-associated risk behaviours, knowledge and seroprevalence of viral infections among people who inject drugs (PWID) in nonurban locales in the US. Harm reduction services are more available in urban locales. The present study examined a cohort of active PWID residing in non urban areas of Connecticut to investigate how primarily injecting in urban or non urban areas was associated with injection-associated risk behaviours, knowledge and prevalence of blood-borne viruses.
We described the sample and performed bivariate and multivariable analyses on injection-associated risk behaviours, HIV/hepatitis/overdose knowledge and baseline serological data to identify differences between individuals who injected primarily in nonurban locales and those who did not.
Harm reduction knowledge and use of harm reduction services were poor in both groups. Those injecting most often in urban settings were 1.88 (1.19, 2.98 95% confidence interval) times more likely to engage in at least one injection-associated risk behaviour than their nonurban counterpart. Seroprevalence rates (23.6% for hepatitis B virus, 39.2% for hepatitis C virus, and 1.1% for HIV) were no different between the two groups.
The data provided little evidence that the benefits of urban harm reduction programs, such as syringe exchange, risk reduction interventions and education programs have penetrated into this nonurban population, even among those who injected in urban locales where such programs exist. Harm reduction interventions for nonurban communities of PWID are needed to reduce HIV and hepatitis B and C transmission. [Grau LB, Zhan W, Heimer R. Prevention knowledge, risk behaviours and seroprevalence among nonurban injectors of southwest Connecticut. Drug Alcohol Rev 2016;35:628-636].
在美国非城市地区,关于注射吸毒者(PWID)中与注射相关的风险行为、病毒感染知识及血清流行率的了解甚少。城市地区提供的减少伤害服务更多。本研究调查了一群居住在康涅狄格州非城市地区的活跃注射吸毒者,以探究主要在城市或非城市地区注射与注射相关风险行为、知识及血源病毒流行率之间的关联。
我们描述了样本,并对与注射相关的风险行为、艾滋病毒/肝炎/过量用药知识及基线血清学数据进行了双变量和多变量分析,以确定主要在非城市地区注射者与非主要在非城市地区注射者之间的差异。
两组的减少伤害知识及减少伤害服务的使用情况均较差。在城市环境中注射最频繁的人从事至少一种与注射相关风险行为的可能性比非城市地区的同行高1.88倍(95%置信区间为1.19至2.98)。两组的血清流行率(乙肝病毒为23.6%,丙肝病毒为39.2%,艾滋病毒为1.1%)并无差异。
数据几乎没有提供证据表明城市减少伤害项目(如注射器交换、风险降低干预措施和教育项目)的益处已渗透到这一非城市人群中,即使是在存在此类项目的城市地区注射的人群中也是如此。需要针对非城市地区的注射吸毒者社区开展减少伤害干预措施,以减少艾滋病毒及乙肝和丙肝的传播。[格劳LB、詹W、海默R。康涅狄格州西南部非城市注射吸毒者的预防知识、风险行为及血清流行率。《药物与酒精评论》2016年;35:628 - 636]