Pollack P F, Adamson C, Koldovsky O
Department of Pediatrics, University of Arizona Health Sciences Center, Tucson 85724.
Experientia. 1989 Apr 15;45(4):385-8. doi: 10.1007/BF01957488.
Because of the presence of bombesin-like immunoreactivity in milk, we investigated if enteral administration of bombesin affects the intestinal luminal content of trypsin and protein in 12-14-day-old rats. Bombesin (40 micrograms/kg), given either orogastrically or subcutaneously, produced a significant elevation in the intestinal content of trypsin activity. Thus, enterally-administered bombesin can produce acute biologic effects in suckling rats.
由于乳汁中存在蛙皮素样免疫反应性，我们研究了给12 - 14日龄大鼠肠内注射蛙皮素是否会影响胰蛋白酶和蛋白质的肠腔含量。经口胃内或皮下给予蛙皮素（40微克/千克），可使胰蛋白酶活性的肠内含量显著升高。因此，肠内给予蛙皮素可在乳鼠中产生急性生物学效应。
