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回顾长效注射剂治疗精神分裂症的疗效。

Reviewing depot injection efficacy in the treatment of schizophrenia.

作者信息

Jones Adrian, Jones Martin

机构信息

Betsi Cadwaladr University Health Board, Mold, North Wales.

Department of Rural Health, University of South Australia, Whyalla, Australia.

出版信息

Nurs Stand. 2016 Apr 13;30(33):50-9. doi: 10.7748/ns.30.33.50.s45.

DOI:10.7748/ns.30.33.50.s45
PMID:27073965
Abstract

Schizophrenia is a severe and enduring mental health disorder. Treatment includes antipsychotic medication and psychological interventions. Medication can be administered as a depot injection; these treatments reduce the risk of relapse in some people with schizophrenia who have difficulties adhering to oral medication regimens. This article outlines the types of depot and medications that are available for the treatment of schizophrenia, and discusses the evidence base supporting their efficacy. The role of antipsychotic medication as part of a treatment plan should be reinforced by enabling patients to make an informed choice about which medication best supports their health and wellbeing.

摘要

精神分裂症是一种严重且持久的心理健康障碍。治疗方法包括抗精神病药物治疗和心理干预。药物可以通过长效注射剂给药;这些治疗方法降低了一些难以坚持口服药物治疗方案的精神分裂症患者复发的风险。本文概述了可用于治疗精神分裂症的长效注射剂类型和药物,并讨论了支持其疗效的证据基础。应通过让患者能够明智地选择哪种药物最能支持他们的健康和福祉,来强化抗精神病药物作为治疗计划一部分的作用。

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Reviewing depot injection efficacy in the treatment of schizophrenia.回顾长效注射剂治疗精神分裂症的疗效。
Nurs Stand. 2016 Apr 13;30(33):50-9. doi: 10.7748/ns.30.33.50.s45.
2
Injections of depot antipsychotic medications in patients suffering from schizophrenia: do they hurt?在精神分裂症患者中注射长效抗精神病药物:会疼吗?
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[French Society for Biological Psychiatry and Neuropsychopharmacology task force: Formal Consensus for the prescription of depot antipsychotics].[法国生物精神病学与神经精神药理学协会特别工作组:长效抗精神病药物处方的正式共识]
Encephale. 2013 Dec;39 Suppl 4:189-203. doi: 10.1016/S0013-7006(13)70121-0.
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Long-term depot antipsychotics. A risk-benefit assessment.长效抗精神病药物。风险效益评估。
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Guidelines for depot antipsychotic treatment in schizophrenia. European Neuropsychopharmacology Consensus Conference in Siena, Italy.精神分裂症长效抗精神病药物治疗指南。意大利锡耶纳欧洲神经精神药理学共识会议。
Eur Neuropsychopharmacol. 1998 Feb;8(1):55-66. doi: 10.1016/s0924-977x(97)00045-x.
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[Is our clinical practice of antipsychotic relapse prevention in schizophrenia really evidence-based].我们在精神分裂症中预防抗精神病药物复发的临床实践真的是以证据为基础的吗?
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Long-acting atypical injectable antipsychotics in the treatment of schizophrenia: safety and tolerability review.长效非典型注射用抗精神病药治疗精神分裂症:安全性和耐受性评价。
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Efficacy and effectiveness of depot versus oral antipsychotics in schizophrenia: synthesizing results across different research designs.长效与口服抗精神病药治疗精神分裂症的疗效和效果:综合不同研究设计的结果。
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