Institute for NanoScience Design, Osaka University , Toyonaka, Osaka 560-8531, Japan.
Anal Chem. 2016 May 3;88(9):4619-23. doi: 10.1021/acs.analchem.6b00515. Epub 2016 Apr 22.
Simple chiral recognition method of 2-alkylalcohols on a silica gel plate was proposed by using the induced circular dichroism (ICD) of J-aggregates of diprotonated tetraphenylporphyrin and magnetic circular dichroism (MCD) spectrometry. To the silica gel on a glass slide including a chiral 2-alkylalcohol and 4 M sulfuric acid, the porphyrin in toluene was added and mixed. Then, the glass slide was used for in situ MCD measurement. The observed ICD spectra could recognize well the chirality of the alcohols and the ICD intensity normalized by the MCD intensity of the J-aggregate correlated linearly to the amount of the chiral alcohols in the silica gel.
提出了一种在硅胶板上通过二质子化四苯基卟啉 J-聚集体的诱导圆二色性（ICD）和磁圆二色性（MCD）光谱对 2-烷基醇进行手性识别的简单方法。在包含手性 2-烷基醇和 4 M 硫酸的载玻片上的硅胶中加入并混合甲苯中的卟啉，然后使用该载玻片进行原位 MCD 测量。观察到的 ICD 光谱可以很好地识别醇的手性，并且通过 J-聚集体的 MCD 强度归一化的 ICD 强度与硅胶中手性醇的量呈线性相关。
