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[在整个孕期接受卡地阿唑的大鼠后代中卡地阿唑的肾小管分泌]

[Tubular secretion of cardiotrast in the progeny of rats receiving it throughout pregnancy].

作者信息

Berkhin E B, Gossen I E

出版信息

Farmakol Toksikol. 1989 Jan-Feb;52(1):48-50.

PMID:2707421
Abstract

Administration of cardiotrast (50-80 mg twice a day subcutaneously) during pregnancy was shown to induce a significant suppression of tubular secretion of the xenobiotic in the offspring. When cardiotrast was given only in the postnatal period, tolerance failed to develop.

摘要

怀孕期间皮下注射泛影葡胺(每天两次,每次50 - 80毫克)显示会显著抑制后代中异生物的肾小管分泌。当仅在出生后阶段给予泛影葡胺时,耐受性未能形成。

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