Rocha-e-Silva Mauricio
Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
Braz J Cardiovasc Surg. 2016 Feb;31(1):45-51. doi: 10.5935/1678-9741.20150065.
Experimental models of human pathology are useful guides to new approaches towards improving clinical and surgical treatments. A systematic search through PubMed using the syntax (shock) AND (trauma) AND (animal model) AND (cardiovascular) AND ("2010/01/01"[PDat]: "2015/12/31"[PDat]) found 88 articles, which were reduced by manual inspection to 43 entries. These were divided into themes and each theme is subsequently narrated and discussed conjointly. Taken together, these articles indicate that valuable information has been developed over the past 5 years concerning endothelial stability, mesenteric lymph, vascular reactivity, traumatic injuries, burn and sepsis. A surviving interest in hypertonic saline resuscitation still exists.
人类病理学实验模型是改进临床和外科治疗新方法的有用指南。使用(休克)AND(创伤)AND(动物模型)AND(心血管)AND(“2010/01/01”[出版日期]:“2015/12/31”[出版日期])的语法在PubMed中进行系统搜索,发现了88篇文章,经人工筛选后减少到43条记录。这些文章被分为不同主题,随后对每个主题进行叙述和联合讨论。综合来看,这些文章表明在过去5年里,已经获得了关于内皮稳定性、肠系膜淋巴、血管反应性、创伤性损伤、烧伤和脓毒症的有价值信息。对高渗盐水复苏仍存在持续的研究兴趣。