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长期使用氯氮平治疗期间的中暑:我们应该担心炎热天气吗?

Heat stroke during long-term clozapine treatment: should we be concerned about hot weather?

作者信息

Hoffmann Maurício Scopel, Oliveira Lucas Mendes, Lobato Maria Inês Rodrigues, Belmonte-de-Abreu Paulo

机构信息

Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.

出版信息

Trends Psychiatry Psychother. 2016 Jan-Mar;38(1):56-9. doi: 10.1590/2237-6089-2015-0066.

DOI:10.1590/2237-6089-2015-0066
PMID:27074342
Abstract

OBJECTIVE

To describe the case of a patient with schizophrenia on clozapine treatment who had an episode of heat stroke.

CASE DESCRIPTION

During a heat wave in January and February 2014, a patient with schizophrenia who was on treatment with clozapine was initially referred for differential diagnose between systemic infection and neuroleptic malignant syndrome, but was finally diagnosed with heat stroke and treated with control of body temperature and hydration.

COMMENTS

This report aims to alert clinicians take this condition into consideration among other differential diagnoses, especially nowadays with the rise in global temperatures, and to highlight the need for accurate diagnosis of clinical events during pharmacological intervention, in order to improve treatment decisions and outcomes.

摘要

目的

描述1例接受氯氮平治疗的精神分裂症患者发生中暑的病例。

病例描述

在2014年1月和2月的热浪期间,1例接受氯氮平治疗的精神分裂症患者最初因全身性感染和抗精神病药恶性综合征的鉴别诊断而被转诊,但最终被诊断为中暑,并接受了体温控制和补液治疗。

评论

本报告旨在提醒临床医生在其他鉴别诊断中考虑这种情况,特别是在全球气温上升的当下,并强调在药物干预期间准确诊断临床事件的必要性,以改善治疗决策和结果。

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