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典型神经性肌萎缩的神经影像学

Neuroimaging of classic neuralgic amyotrophy.

作者信息

Lieba-Samal Doris, Jengojan Suren, Kasprian Gregor, Wöber Christian, Bodner Gerd

机构信息

Department of Neurology, Medical University of Vienna, Währinger Gürtel 18-20 1090, Vienna, Austria.

Department of Radiology and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.

出版信息

Muscle Nerve. 2016 Dec;54(6):1079-1085. doi: 10.1002/mus.25147. Epub 2016 Sep 23.

Abstract

INTRODUCTION

Neuralgic amyotrophy (NA) often imposes diagnostic problems. Recently, MRI and high-resolution ultrasound (HRUS) have proven useful in diagnosing peripheral nerve disorders.

METHODS

We performed a chart and imaging review of patients who were examined using neuroimaging and who were referred because of clinically diagnosed NA between March 1, 2014 and May 1, 2015.

RESULTS

Six patients were included. All underwent HRUS, and 5 underwent MRI. Time from onset to evaluation ranged from 2 weeks to 6 months. HRUS showed segmental swelling of all clinically affected nerves/trunks. Atrophy of muscles was detected in those assessed >1 month after onset. MRI showed T2-weighted hyperintensity in all clinically affected nerves, except for the long thoracic nerve, and denervation edema of muscles.

CONCLUSIONS

HRUS and MRI are valuable diagnostic tools in NA. This could change the diagnostic approach from one now focused on excluding other disorders to confirming NA through imaging markers. Muscle Nerve 54: 1079-1085, 2016.

摘要

引言

神经性肌萎缩(NA)常常带来诊断难题。近来,磁共振成像(MRI)和高分辨率超声(HRUS)已被证明在诊断周围神经疾病方面很有用。

方法

我们对2014年3月1日至2015年5月1日期间因临床诊断为NA而接受神经影像学检查并被转诊的患者进行了病历和影像学回顾。

结果

纳入6例患者。所有患者均接受了HRUS检查,5例接受了MRI检查。从发病到评估的时间为2周 至6个月。HRUS显示所有临床受累神经/神经干节段性肿胀。在发病1个月后接受评估的患者中检测到肌肉萎缩。MRI显示除胸长神经外,所有临床受累神经在T2加权像上呈高信号,以及肌肉失神经水肿。

结论

HRUS和MRI是NA中有价值 的诊断工具。这可能会改变诊断方法,从目前专注于排除其他疾病转变为通过影像学标志物来确诊NA。《肌肉与神经》54: 1079 - 1085, 2016年。

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