Gunnar M R, Connors J, Isensee J
Institute of Child Development, University of Minnesota, Minneapolis 55455.
Dev Psychobiol. 1989 Apr;22(3):221-33. doi: 10.1002/dev.420220304.
The purpose of the study was to examine the stability of the adrenocortical response to stimulation in the human neonate. Forty-nine healthy newborns were examined twice responding to discharge examinations performed on two consecutive days. The dependent measures were salivary and plasma cortisol and behavioral state. Little evidence of stability was obtained. Instead, the results showed significant elevations in cortisol only in response to the first discharge examination. No significant elevation in cortisol was noted to the second discharge examination although the newborns continued to exhibit behavioral distress. Time since delivery was not a significant factor in producing these results. The findings are discussed with regard to neonatal coping processes and the importance of novelty in regulating increases in adrenocortical activity.
该研究的目的是检验人类新生儿肾上腺皮质对刺激反应的稳定性。49名健康新生儿在连续两天进行出院检查时接受了两次检查。相关测量指标为唾液和血浆皮质醇以及行为状态。几乎没有获得稳定性的证据。相反，结果显示仅在首次出院检查时皮质醇有显著升高。尽管新生儿持续表现出行为窘迫，但第二次出院检查时未发现皮质醇有显著升高。分娩后的时间不是产生这些结果的重要因素。结合新生儿应对过程以及新奇性在调节肾上腺皮质活动增加中的重要性对这些发现进行了讨论。
