羊膜移植联合氩激光光凝术与羊膜移植联合组织清创术治疗真菌性角膜炎的对比研究
Amniotic Membrane Graft with Argon Laser Photocoagulation Versus Amniotic Membrane Graft with Tissue Debridement for Treatment of Mycotic Keratitis.
作者信息
Khater Mohammad M
机构信息
a Ophthalmology Department , Tanta University Hospital , Gharbia, Egypt.
出版信息
Semin Ophthalmol. 2017;32(3):348-352. doi: 10.3109/08820538.2015.1090613. Epub 2016 Apr 14.
AIM
To compare augmented therapy with argon laser and amniotic membrane graft (AMG) versus AMG and tissue debridement for resistant mycotic corneal ulcers.
METHODS
This study included 40 cases of resistant fungal corneal ulcers in two groups. In one group, argon laser photocoagulation and AMG were done while AMG with tissue debridement was done as adjunctive therapy for the specific antifungal agents.
RESULTS
Complete healing with no adverse effects was achieved in argon laser group in duration ranging from 2-3 weeks in all cases. In the AMG group, duration of healing ranged from 3-5 weeks. Visual acuity was improved with one or more line gain in eight cases (40%) in the laser group, while in six cases (30%) only in the AMG group.
CONCLUSIONS
Augmented therapy with argon laser and AMG is superior to AMG with tissue debridement for treatment of resistant fungal corneal ulcers.
目的
比较氩激光联合羊膜移植（AMG）增强治疗与AMG联合组织清创术治疗耐药真菌性角膜溃疡的效果。
方法
本研究纳入40例耐药真菌性角膜溃疡患者，分为两组。一组采用氩激光光凝联合AMG治疗，另一组采用AMG联合组织清创术作为特定抗真菌药物的辅助治疗。
结果
氩激光组所有病例均在2 - 3周内完全愈合，无不良反应。AMG组愈合时间为3 - 5周。激光组8例（40%）视力提高一行或多行，而AMG组仅6例（30%）。
结论
氩激光联合AMG增强治疗在治疗耐药真菌性角膜溃疡方面优于AMG联合组织清创术。
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