Bhatia K, Jenkins C, Prasad M, Koki G, Lombange J
Hum Biol. 1989 Feb;61(1):45-64.
We have examined the HLA profiles of the Hagahai and the Haruai people, two linguistic groups in the remote western Schrader mountains who have only recently had administrative contact, and compared them with those of other populations in Papua New Guinea. None of the antigens detected in the two groups was found missing in other populations although significant differences in allele frequencies exist. Recent contact history does not appear to have played any significant role in shaping these differences. Similarly, no evidence of differential selection pressures contributing to HLA heterogeneity was found. The genetic profiles of the Hagahai and the Haruai appear to be a result of recent admixture between unrelated, genetically disparate groups.
我们研究了哈加海人和哈鲁艾人的HLA基因谱，这两个语言群体位于偏远的西部施拉德山脉，直到最近才有行政上的接触，并且将他们的基因谱与巴布亚新几内亚其他人群的进行了比较。尽管等位基因频率存在显著差异，但在这两个群体中检测到的抗原在其他人群中均未发现缺失。近期的接触历史似乎在形成这些差异方面没有发挥任何重要作用。同样，也没有发现导致HLA异质性的差异选择压力的证据。哈加海人和哈鲁艾人的基因谱似乎是近期不相关的、基因差异较大的群体之间混合的结果。
