Ertugrul Ilker, Karagoz Tevfik, Celiker Alpay, Alehan Dursun, Ozer Sema, Ozkutlu Suheyla
Division of Pediatric Cardiology, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Division of Pediatric Cardiology, Department of Pediatrics, Faculty of Medicine, Koc University, Ankara, Turkey.
Congenit Heart Dis. 2016 Dec;11(6):584-588. doi: 10.1111/chd.12340. Epub 2016 Apr 14.
This study aims to determine efficacy and safety of rapid left ventricular pacing (RLVP) during balloon aortic valvuloplasty and effect on development of postprocedural aortic insufficiency (AI) in children.
This is a retrospective comparison of 56 children (mean age 18.3 month; 1 day-15 years of age) who underwent valvuloplasty by using RLVP with standard method (without pacing) during same time period (74 children; mean age 12.6 month; 1 day-18 years of age).
The systolic valvular gradient decreased from a mean 67 ± 20.4 mm Hg (26-120 mm Hg) before the procedure to a mean 27.6 ± 17.8 mm Hg (0-120 mm Hg) after the procedure. Procedure failed in two of the patients (3.6%) who received the RLVP; only two patients developed severe AI. Among those patients who underwent the standard method procedure failed in 6 patients (8.3%), whereas severe AI was seen in 15 (20.2%). RLVP decreased the incidence of postprocedure severe AI significantly (P < .01) but it had no effect on the gradient reduction of the procedure (P > .05). RLVP did not change the procedure duration, but decreased the duration of fluoroscopy significantly (P < .01).
RLVP can be used effectively and safely for pacing during balloon aortic valvuloplasty procedures in all age groups; it decreases procedural failure rate, eases the procedure and prevents the development of AI through the stabilization of the balloon.
本研究旨在确定在儿童球囊主动脉瓣成形术中快速左心室起搏(RLVP)的有效性和安全性,以及其对术后主动脉瓣关闭不全(AI)发生发展的影响。
这是一项回顾性比较研究,比较了56例儿童(平均年龄18.3个月;年龄范围1天至15岁),他们在同一时期接受了使用RLVP的瓣膜成形术,与标准方法(无起搏)组(74例儿童;平均年龄12.6个月;年龄范围1天至18岁)进行对比。
收缩期瓣膜压差从术前平均67±20.4 mmHg(26 - 120 mmHg)降至术后平均27.6±17.8 mmHg(0 - 120 mmHg)。接受RLVP的患者中有2例(3.6%)手术失败;仅2例患者发生严重AI。在接受标准方法的患者中,6例(8.3%)手术失败,而15例(20.2%)出现严重AI。RLVP显著降低了术后严重AI的发生率(P < 0.01),但对手术压差降低无影响(P > 0.05)。RLVP未改变手术持续时间,但显著缩短了透视时间(P < 0.01)。
RLVP可有效且安全地用于各年龄组儿童球囊主动脉瓣成形术中的起搏;它可降低手术失败率,简化手术操作,并通过稳定球囊防止AI的发生发展。