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用于治疗深部眶周婴儿血管瘤的0.5%马来酸噻吗洛尔滴眼液

Topical timolol maleate 0.5% solution for the management of deep periocular infantile hemangiomas.

作者信息

Painter Sally L, Hildebrand Göran Darius

机构信息

Department of Pediatric Ophthalmology, Royal Berkshire Hospital, Reading, and King Edward VII Hospital, Windsor, United Kingdom.

Department of Pediatric Ophthalmology, Royal Berkshire Hospital, Reading, and King Edward VII Hospital, Windsor, United Kingdom.

出版信息

J AAPOS. 2016 Apr;20(2):172-174.e1. doi: 10.1016/j.jaapos.2015.11.012.

Abstract

This retrospective, consecutive, clinical case series examined the use of topical timolol in the treatment of 5 children with deep, periocular infantile hemangiomas that caused astigmatism, change in head posture, or ptosis. All patients were treated with timolol maleate solution 0.5% twice daily until the lesions had regressed. All 5 children showed regression of the lesion and improvement in amblyogenic risk factors within 2 weeks.

摘要

本回顾性、连续性临床病例系列研究了局部应用噻吗洛尔治疗5例患有深部眶周婴儿血管瘤的儿童,这些血管瘤导致了散光、头位改变或上睑下垂。所有患者均接受0.5%马来酸噻吗洛尔溶液治疗,每日两次,直至病变消退。所有5名儿童在2周内病变均出现消退,且致弱视危险因素有所改善。

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