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在危地马拉农村偏远地区使用普萘洛尔治疗大面积面部婴幼儿血管瘤。

Use of propranolol in a remote region of rural Guatemala to treat a large facial infantile haemangioma.

作者信息

Goldberg Vera, Martinez Boris, Cnop Katia, Rohloff Peter

机构信息

Harvard Medical School, Boston, Massachusetts, USA.

Wuqu' Kawoq, Santiago Sacatepéquez, Guatemala.

出版信息

BMJ Case Rep. 2017 May 16;2017:bcr-2017-219782. doi: 10.1136/bcr-2017-219782.

Abstract

We present a female infant with a right-sided facial and neck haemangioma, from a remote, resource-poor community in rural Guatemala. She received first-line treatment, propranolol, with marked reduction in tumour size and erythema. Treatment was stopped after 35 weeks due to recurrent diarrhoea and sustained weight loss. Propranolol can be used to safely treat infants with haemangiomas in remote, rural communities if there is adequate follow-up, education and communication. Periocular haemangiomas should be treated promptly to avoid visual impairment. Infants with large facial haemangiomas should be screened for osterior fossa anomalies, emangioma, rterial anomalies, ardiac anomalies, and ye anomalies (PHACE) syndrome, and specialists should be involved. The case also highlights the difficulty of providing treatment for a complex illness when basic health needs, such as food security and water sanitation, are limited.

摘要

我们介绍了一名来自危地马拉农村偏远、资源匮乏社区的患有右侧面部和颈部血管瘤的女婴。她接受了一线治疗药物普萘洛尔,肿瘤大小和红斑明显减小。由于反复腹泻和持续体重减轻,治疗在35周后停止。如果有足够的随访、教育和沟通,普萘洛尔可用于安全治疗偏远农村社区患有血管瘤的婴儿。眼周血管瘤应及时治疗以避免视力损害。患有大型面部血管瘤的婴儿应筛查后颅窝异常、血管瘤、动脉异常、心脏异常和眼部异常(PHACE)综合征,且应由专家参与诊治。该病例还凸显了在粮食安全和水卫生等基本健康需求有限的情况下,为复杂疾病提供治疗的困难。

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