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79例慢性蝶窦炎经鼻经口蝶窦切开术的结果

Results of transnasal transostial sphenoidotomy in 79 cases of chronic sphenoid sinusitis.

作者信息

Massoubre J, Saroul N, Vokwely J-E, Lietin B, Mom T, Gilain L

机构信息

Service ORL et chirurgie cervico-faciale, CHU, université d'Auvergne, 58, rue Montalembert, 63000 Clermont-Ferrand, France.

Service ORL et chirurgie cervico-faciale, centre hospitalier Essos, Yaoundé, Cameroon.

出版信息

Eur Ann Otorhinolaryngol Head Neck Dis. 2016 Sep;133(4):231-6. doi: 10.1016/j.anorl.2016.02.002. Epub 2016 Apr 11.

Abstract

OBJECTIVE

This study was designed to retrospectively review the postoperative results of transnasal transostial sphenoidotomy in 79 patients with isolated chronic sphenoid sinusitis operated between 1995 and 2013 and evaluate the recurrence rate due to postoperative closure of the sphenoidotomy.

PATIENTS AND METHODS

Seventy-nine patients, 44 women and 35 men (M:F sex ratio: 0.79) aged 10 to 84 years (mean age: 48), were included. The most common presenting symptom was headache in 61% of cases. Visual disturbances were present in three cases. The diagnostic work-up comprised nasal endoscopy, computed tomography (CT) and magnetic resonance imaging (MRI) of the sinuses. The surgical indication was based on failure of antibiotic therapy and/or the nature and severity of sphenoid sinusitis. All patients were operated by endoscopic transnasal transostial sphenoidotomy. Samples were taken for histological, bacteriological and mycological examination.

RESULTS

No intraoperative or immediate postoperative complications were observed. Nature of the lesion: forty-seven patients (59.5%) presented nonspecific inflammatory lesions with negative bacterial or fungal culture and inflammatory mucosal changes, 19 patients (24%) had fungal sinusitis presenting as a fungus ball and 13 patients (16.4%) had documented bacterial sinusitis. Mean postoperative follow-up was 7.4 months (range: 6-48). No recurrence of the sinusitis or symptoms was observed in 71 cases (89.8%). Recurrence: eight cases (10.2%) of postoperative closure of the sphenoidotomy were observed, requiring one (6 cases) or several (2 cases) reoperations with a mean of 16.4 months after the initial procedure. Symptoms of recurrence consisted of varying degrees of headache, with similar symptoms to those of the first episode in 7 cases, and retro-orbital headache in 1 case. Reoperation was performed via a transnasal transostial approach in 6 cases and a transethmoidal approach in 2 cases.

CONCLUSION

The transnasal transostial surgical approach is a safe and effective procedure for the treatment of isolated sphenoid sinusitis. However, the recurrence rate due to postoperative closure of the sphenoidotomy observed in our series raises the question of postoperative maintenance of a patent and functional sphenoidotomy.

摘要

目的

本研究旨在回顾性分析1995年至2013年间接受经鼻经口蝶窦切开术的79例孤立性慢性蝶窦炎患者的术后结果,并评估蝶窦切开术后闭合导致的复发率。

患者与方法

纳入79例患者,其中女性44例,男性35例(男女比例为0.79),年龄10至84岁(平均年龄48岁)。最常见的症状是头痛,占61%的病例。3例出现视觉障碍。诊断检查包括鼻窦鼻内镜检查、计算机断层扫描(CT)和磁共振成像(MRI)。手术指征基于抗生素治疗失败和/或蝶窦炎的性质及严重程度。所有患者均接受内镜经鼻经口蝶窦切开术。采集样本进行组织学、细菌学和真菌学检查。

结果

未观察到术中或术后即刻并发症。病变性质:47例(59.5%)表现为非特异性炎性病变,细菌或真菌培养阴性且有炎性黏膜改变;19例(24%)为真菌性鼻窦炎,表现为真菌球;13例(16.4%)有细菌性鼻窦炎记录。术后平均随访7.4个月(范围:6至48个月)。71例(89.8%)未观察到鼻窦炎或症状复发。复发情况:观察到8例(10.2%)蝶窦切开术后闭合,其中6例需要再次手术1次,2例需要多次手术,初次手术后平均16.4个月再次手术。复发症状包括不同程度的头痛,7例症状与首次发作相似,1例为眶后头痛。6例再次手术采用经鼻经口入路,2例采用经筛窦入路。

结论

经鼻经口手术入路是治疗孤立性蝶窦炎的一种安全有效的方法。然而,我们系列研究中观察到的蝶窦切开术后闭合导致的复发率,引发了蝶窦切开术后保持开放和功能通畅的问题。

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