Greiwe Justin, Bernstein Jonathan A
Bernstein Allergy Group, 8444 Winton Rd, Cincinnati, OH 45231, USA; Division of Allergy, Immunology and Rheumatology, University of Cincinnati, 231 Albert Sabin Way, Cincinnati, OH 45267, USA.
Bernstein Allergy Group, 8444 Winton Rd, Cincinnati, OH 45231, USA; Division of Allergy, Immunology and Rheumatology, University of Cincinnati, 231 Albert Sabin Way, Cincinnati, OH 45267, USA.
Immunol Allergy Clin North Am. 2016 May;36(2):289-303. doi: 10.1016/j.iac.2015.12.006. Epub 2016 Mar 12.
Nonallergic rhinitis (NAR) is one of the most common conditions in medicine, affecting the quality of life of millions of patients throughout the United States. Despite its ubiquitous nature, NAR remains a poorly managed and often difficult to treat condition. NAR is often suboptimally managed by clinicians with poor clinical outcomes. Establishing the correct diagnosis requires a keen understanding of the unique underlying mechanisms involved in NAR, which is still evolving. Ultimately epidemiologic studies that better define NAR prevalence and its economic burden on society are needed to convince funding agencies of the need for research to elucidate mechanisms and specific treatment approaches for this condition.
非过敏性鼻炎(NAR)是医学上最常见的病症之一,影响着美国数百万患者的生活质量。尽管其普遍存在,但NAR仍然是一种管理不善且通常难以治疗的病症。临床医生对NAR的管理往往欠佳,临床效果不佳。要做出正确诊断,需要深入了解NAR所涉及的独特潜在机制,而这一机制仍在不断演变。最终,需要开展流行病学研究,以更准确地界定NAR的患病率及其对社会的经济负担,从而让资助机构认识到有必要进行研究,以阐明该病症的发病机制和具体治疗方法。