Herard C, Arnaud D, Goga D, Rousseau P, Potier B
Department of plastic, reconstructive and aesthetic surgery, hôpital Trousseau, CHU de Tours, avenue de la République, 37170 Chambray-Lès-Tours, France.
Department of plastic, reconstructive and aesthetic surgery, CHU d'Angers, 4, rue Larrey, 49933 Angers, France.
Ann Dermatol Venereol. 2016 Jun-Jul;143(6-7):457-61. doi: 10.1016/j.annder.2015.03.027. Epub 2016 Apr 12.
Squamous cell carcinomas are malignant tumours of epithelial origin that can appear on sites subjected to chronic inflammation after a period of several years. The rapid development of squamous cell carcinoma at the donor site for a thin skin graft is a rare and poorly understood situation.
We report the case of a patient undergoing thin skin grafting to cover the area of removal of a vertex squamous cell carcinoma and in whom squamous cell carcinoma appeared at the donor site within 9 weeks.
In our case, we ruled out intraoperative contamination because two sets of surgical instruments were used. Given the number of cases reported in the literature, a chance event seems unlikely. The hypothesis of an acute inflammatory process caused by scarring of the thin skin graft site appears to us the most convincing. Development of cancer at the graft donor site may thus be added to the list of complications of thin skin grafting.
鳞状细胞癌是上皮起源的恶性肿瘤，数年后可出现在遭受慢性炎症的部位。薄皮片供皮区鳞状细胞癌的快速发展是一种罕见且了解甚少的情况。
我们报告了一例接受薄皮片移植以覆盖头顶鳞状细胞癌切除区域的患者，该患者在9周内供皮区出现了鳞状细胞癌。
在我们的病例中，由于使用了两套手术器械，我们排除了术中污染。鉴于文献报道的病例数量，偶然事件似乎不太可能。薄皮片移植部位瘢痕形成引起急性炎症过程的假说在我们看来最有说服力。因此，移植供皮区发生癌症可能被列入薄皮片移植的并发症清单。
