Castellanos-González María, Picazo Talavera María Remedios
Servicio de Dermatología y Venereología, Hospital del Sureste, Arganda del Rey, Madrid, España.
Servicio de Reumatología, Hospital del Sureste, Arganda del Rey, Madrid, España.
Med Clin (Barc). 2016 Sep 16;147(6):257-61. doi: 10.1016/j.medcli.2016.02.028. Epub 2016 Apr 12.
Sarcoidosis is an idiopathic multisystem granulomatous disease that commonly involves the skin in 25% of affected patients. Because lesions assume a vast array of morphologies, a classification dividing them into specific (with presence of typical granulomas in the biopsy) or nonspecific (not containing granulomas) has been proposed. In the first group the variant morpheaform is considered exceptional. We review the cases reported in the literature and describe the possible differential diagnosis. We highlight the importance of recognizing the very atypical presentation of sarcoidosis and its ability to mimic morpheaform or sclerosis diseases in our patients.
结节病是一种特发性多系统肉芽肿性疾病,25%的受累患者通常会累及皮肤。由于病变呈现出多种多样的形态,因此有人提出将其分为特异性(活检中有典型肉芽肿)或非特异性(不包含肉芽肿)两类。在第一组中,硬斑病样变体被认为是罕见的。我们回顾了文献中报道的病例并描述了可能的鉴别诊断。我们强调认识结节病非常不典型的表现及其在我们患者中模仿硬斑病样或硬化性疾病的能力的重要性。