Yamamoto Umpei, Nishizaka Mari, Yoshimura Chikara, Kawagoe Nobutoshi, Hayashi Atsumi, Kadokami Toshiaki, Ando Shin-Ichi
Sleep Apnea Center, Kyushu University Hospital, Japan.
Intern Med. 2016;55(8):901-5. doi: 10.2169/internalmedicine.55.5769. Epub 2016 Apr 15.
We assessed the prevalence of sleep disordered breathing (SDB) and characteristics among patients who visited a urology clinic complaining of nocturia (URO group) and those who visited a sleep apnea (SA) clinic complaining of excessive daytime sleepiness (EDS) (SA group). Additionally, we evaluated the effects of continuous positive airway pressure (CPAP) therapy in the URO group patients with nocturia and SDB resistant to conventional therapy for nocturia.
Questionnaires were used to assess EDS, nocturia and lower urinary tract symptoms in 34 URO group patients and 49 age-matched SA group patients. We also compared these factors in the male patients in both groups and the male and female patients in the SA group. Significant SDB was diagnosed as a 3% oxygen desaturation index (3%ODI) on pulse oximeter of >5/h. The treatment response was analyzed in six URO group patients treated with CPAP after not responding to the conventional medical treatment.
SDB was found in 91.8% of the SA group patients and 70.6% of the URO group patients. The level of EDS and lower urinary tract symptoms were similar in both groups. The SA group showed higher 3%ODI values, while the frequency of urination during bedtime was higher in the URO group. The frequency of nocturnal urination was reduced after CPAP in the subjects resistant to conventional therapy.
SDB is as prevalent in patients who visit a urology clinic complaining of nocturia as in those who visit a sleep apnea clinic. Patients who complains of nocturia must be assessed for SDB before starting therapy for nocturia.
我们评估了因夜尿症就诊于泌尿外科诊所的患者(泌尿外科组)和因日间过度嗜睡(EDS)就诊于睡眠呼吸暂停(SA)诊所的患者(SA组)中睡眠呼吸障碍(SDB)的患病率及特征。此外,我们评估了持续气道正压通气(CPAP)治疗对泌尿外科组中夜尿症且对夜尿症常规治疗耐药的SDB患者的疗效。
通过问卷调查评估了34例泌尿外科组患者和49例年龄匹配的SA组患者的EDS、夜尿症及下尿路症状。我们还比较了两组男性患者以及SA组中男性和女性患者的这些因素。显著SDB被诊断为脉搏血氧仪上的氧去饱和指数(3%ODI)>5次/小时。对6例经常规药物治疗无效后接受CPAP治疗的泌尿外科组患者的治疗反应进行了分析。
SA组患者中91.8%存在SDB,泌尿外科组患者中70.6%存在SDB。两组的EDS水平和下尿路症状相似。SA组的3%ODI值更高,而泌尿外科组患者睡前排尿频率更高。对常规治疗耐药的受试者在接受CPAP治疗后夜间排尿频率降低。
因夜尿症就诊于泌尿外科诊所的患者中SDB的患病率与因睡眠呼吸暂停就诊于睡眠呼吸暂停诊所的患者相似。主诉夜尿症的患者在开始夜尿症治疗前必须评估是否存在SDB。