Galgano Michael A, Cantu Robert, Chin Lawrence S
Neurosurgery, SUNY Upstate Medical University.
Neurosurgery, Emerson Hospital.
Cureus. 2016 Mar 14;8(3):e532. doi: 10.7759/cureus.532.
Chronic traumatic encephalopathy (CTE) is a devastating neuropsychological condition afflicting a small percentage of athletes partaking in high-impact sports. The onset of symptoms lags years behind the inciting events. Repetitive minor head injuries are felt to be the main etiology behind CTE. Routine radiographic imaging generally is unremarkable in cases of CTE. Functional magnetic resonance imaging (fMRI), magnetic resonance spectroscopy (MRS), and diffusion tensor imaging (DTI) are advanced MRI-based sequences that have shown promise in detecting early radiographic findings that may be reflective of CTE. Progressive neuronal loss is the histopathological hallmark of this neurodegenerative disease. Strategizing earlier detection techniques is paramount in delivering optimal care to athletes afflicted with CTE.
慢性创伤性脑病(CTE)是一种极具破坏性的神经心理疾病,影响着一小部分从事高强度运动的运动员。症状的出现比引发事件滞后数年。反复的轻度头部损伤被认为是CTE背后的主要病因。在CTE病例中,常规的放射影像学检查通常无明显异常。功能磁共振成像(fMRI)、磁共振波谱(MRS)和扩散张量成像(DTI)是基于磁共振成像的先进序列,在检测可能反映CTE的早期放射学表现方面已显示出前景。进行性神经元丧失是这种神经退行性疾病的组织病理学标志。制定早期检测技术对于为患有CTE的运动员提供最佳护理至关重要。