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慢性创伤性脑病:对运动员的影响

Chronic Traumatic Encephalopathy: The Impact on Athletes.

作者信息

Galgano Michael A, Cantu Robert, Chin Lawrence S

机构信息

Neurosurgery, SUNY Upstate Medical University.

Neurosurgery, Emerson Hospital.

出版信息

Cureus. 2016 Mar 14;8(3):e532. doi: 10.7759/cureus.532.

DOI:10.7759/cureus.532
PMID:27088064
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4831982/
Abstract

Chronic traumatic encephalopathy (CTE) is a devastating neuropsychological condition afflicting a small percentage of athletes partaking in high-impact sports. The onset of symptoms lags years behind the inciting events. Repetitive minor head injuries are felt to be the main etiology behind CTE. Routine radiographic imaging generally is unremarkable in cases of CTE. Functional magnetic resonance imaging (fMRI), magnetic resonance spectroscopy (MRS), and diffusion tensor imaging (DTI) are advanced MRI-based sequences that have shown promise in detecting early radiographic findings that may be reflective of CTE. Progressive neuronal loss is the histopathological hallmark of this neurodegenerative disease. Strategizing earlier detection techniques is paramount in delivering optimal care to athletes afflicted with CTE.

摘要

慢性创伤性脑病(CTE)是一种极具破坏性的神经心理疾病,影响着一小部分从事高强度运动的运动员。症状的出现比引发事件滞后数年。反复的轻度头部损伤被认为是CTE背后的主要病因。在CTE病例中,常规的放射影像学检查通常无明显异常。功能磁共振成像(fMRI)、磁共振波谱(MRS)和扩散张量成像(DTI)是基于磁共振成像的先进序列,在检测可能反映CTE的早期放射学表现方面已显示出前景。进行性神经元丧失是这种神经退行性疾病的组织病理学标志。制定早期检测技术对于为患有CTE的运动员提供最佳护理至关重要。

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本文引用的文献

1
The spectrum of neurobehavioral sequelae after repetitive mild traumatic brain injury: a novel mouse model of chronic traumatic encephalopathy.重复性轻度创伤性脑损伤后神经行为后遗症谱:一种慢性创伤性脑病的新型小鼠模型
J Neurotrauma. 2014 Jul 1;31(13):1211-24. doi: 10.1089/neu.2013.3255. Epub 2014 Jun 12.
2
Imaging of tau pathology in a tauopathy mouse model and in Alzheimer patients compared to normal controls.tau 病小鼠模型和阿尔茨海默病患者与正常对照的 tau 病理学成像比较。
Neuron. 2013 Sep 18;79(6):1094-108. doi: 10.1016/j.neuron.2013.07.037.
3
Chronic traumatic encephalopathy - neuropathology in athletes and war veterans.慢性创伤性脑病——运动员和退伍军人的神经病理学
Neurol Res. 2013 Apr;35(3):290-9. doi: 10.1179/1743132813Y.0000000177.
4
PET scanning of brain tau in retired national football league players: preliminary findings.对退役国家橄榄球联盟球员大脑 tau 的正电子发射断层扫描:初步研究结果。
Am J Geriatr Psychiatry. 2013 Feb;21(2):138-44. doi: 10.1016/j.jagp.2012.11.019. Epub 2013 Jan 22.
5
Acute and chronic changes in diffusivity measures after sports concussion.运动性脑震荡后扩散测量的急性和慢性变化。
J Neurotrauma. 2011 Oct;28(10):2049-59. doi: 10.1089/neu.2011.1836. Epub 2011 Oct 4.
6
A critical review of neuroimaging applications in sports concussion.对神经影像学在运动性脑震荡中的应用的批判性综述。
Curr Sports Med Rep. 2011 Jan-Feb;10(1):14-20. doi: 10.1249/JSR.0b013e31820711b8.
7
Chronic traumatic encephalopathy in a professional American wrestler.一名美国职业摔跤运动员的慢性创伤性脑病
J Forensic Nurs. 2010 Fall;6(3):130-6. doi: 10.1111/j.1939-3938.2010.01078.x.
8
A unified science of concussion.脑震荡的统一科学。
Ann N Y Acad Sci. 2010 Oct;1208(1):58-66. doi: 10.1111/j.1749-6632.2010.05695.x.
9
TDP-43 proteinopathy and motor neuron disease in chronic traumatic encephalopathy.TDP-43 蛋白病与慢性创伤性脑病中的运动神经元病。
J Neuropathol Exp Neurol. 2010 Sep;69(9):918-29. doi: 10.1097/NEN.0b013e3181ee7d85.
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