Lee Do Kyeong, Muraszko Karin, Ulrich Beverly D
Infant Action Lab (Dr Lee), Department of Psychology, New York University, New York; Department of Neurosurgery (Dr Muraszko), School of Medicine, University of Michigan, Ann Arbor, Michigan; Developmental Neuromotor Control Laboratory (Dr Ulrich), School of Kinesiology, University of Michigan, Ann Arbor, Michigan.
Pediatr Phys Ther. 2016 Spring;28(1):24-32. doi: 10.1097/PEP.0000000000000217.
To study development of bone mineral content (BMC) in infants with myelomeningocele (MMC) who did or did not receive upright supported stepping practice (USSP) and in infants with typical development (TD).
We tested 36 infants across the ages of 1 to 18 months. Dual-energy x-ray absorptiometry was used to collect raw BMC data for the whole body, legs, and arms, which were normalized using anthropometrics.
Whole-body BMC generally increased with age; values for infants with MMC were slightly lower than those for infants with TD. Bone mineral content for legs and arms was lower for infants with MMC than for infants with TD. Between MMC groups, the group receiving USSP showed increases in BMC with age.
Bone mineralization in infants with MMC begins to lag compared with infants with TD across infancy, and daily USSP can improve BMC as early as the first year of life.
研究接受或未接受直立支撑踏步练习(USSP)的脊髓脊膜膨出(MMC)婴儿以及发育正常(TD)婴儿的骨矿物质含量(BMC)的发育情况。
我们测试了36名年龄在1至18个月之间的婴儿。使用双能X线吸收法收集全身、腿部和手臂的原始BMC数据,并使用人体测量学方法进行标准化。
全身BMC一般随年龄增长而增加;MMC婴儿的值略低于TD婴儿。MMC婴儿腿部和手臂的骨矿物质含量低于TD婴儿。在MMC组之间,接受USSP的组BMC随年龄增长而增加。
与TD婴儿相比,MMC婴儿在整个婴儿期的骨矿化开始滞后,并且每日USSP最早在生命的第一年就能改善BMC。