Riaz B K, Chowdhury S H, Karim M N, Feroz S, Selim S, Rahman M R
Bangladesh Med Res Counc Bull. 2015 Apr;41(1):29-34. doi: 10.3329/bmrcb.v41i1.30231.
The risk factor profiles, management and outcome have significant difference between stroke subsets. Aim of this study was to investigate the risk for the two most common subtypes of stroke in Bangladeshi population. Seventy cases of hemorrhagic stroke (HS) and 105 cases of confirmed ischemic stroke (IS) were recruited from the Shaheed Suhrawardy Medical College Hospital (ShSMCH) and Dhaka Medical College Hospital between January-June 2011. Total 171 age, sex matched controls were selected from the hospitalized patients with history of no stroke ever. Average hemorrhagic stroke patients (60.4 ± 12.3 years) were younger than both ischemic strokes (63.5 ± 13 years). Family history of premature cardiovascular death was found more in HS patients (p = 0.001). Multivariate logistic regression showed, in IS model 'less fruit consumption (OR 4.6), table salt intake (OR 8.15), psychosocial stress (OR 3.5), abnormal ECG (OR 3.6) and Increased WHR (OR 6.9) appeared as significant predictors adjusted for all potential candidate confounders. In HS model less fruit consumption (OR 5.0), table salt intake (OR 9.9), Stress (OR 4.1), family history of cardiovascular disease (CVD) death (OR 11.3), hypertension (OR 43), aspirin intake (OR 4.5) and increased WHR (OR 3.7) remained as significant predictors.
不同类型的中风在危险因素分布、管理及预后方面存在显著差异。本研究旨在调查孟加拉人群中两种最常见中风亚型的风险。2011年1月至6月期间,从谢赫·苏赫拉瓦迪医学院医院(ShSMCH)和达卡医学院医院招募了70例出血性中风(HS)患者和105例确诊的缺血性中风(IS)患者。从无中风病史的住院患者中选取了171名年龄和性别匹配的对照。出血性中风患者的平均年龄(60.4±12.3岁)比缺血性中风患者(63.5±13岁)年轻。HS患者中过早发生心血管死亡的家族史更为常见(p = 0.001)。多因素逻辑回归显示,在IS模型中,经所有潜在候选混杂因素校正后,“水果摄入量少(OR 4.6)、食盐摄入量(OR 8.15)、心理社会压力(OR 3.5)、心电图异常(OR 3.6)和腰臀比增加(OR 6.9)”是显著的预测因素。在HS模型中,水果摄入量少(OR 5.0)、食盐摄入量(OR 9.9)、压力(OR 4.1)、心血管疾病(CVD)死亡家族史(OR 11.3)、高血压(OR 43)、阿司匹林摄入量(OR 4.5)和腰臀比增加(OR 3.7)仍是显著的预测因素。