Wigneswaran Vinoth, Amador Cristina Isabel, Jelsbak Lotte, Sternberg Claus, Jelsbak Lars
Department of Systems Biology, Technical University of Denmark, Kgs. Lyngby, Denmark.
Department of Science and Environment, Roskilde University, Roskilde, Denmark.
F1000Res. 2016 Mar 31;5. doi: 10.12688/f1000research.7876.1. eCollection 2016.
Microbial activities are most often shaped by interactions between co-existing microbes within mixed-species communities. Dissection of the molecular mechanisms of species interactions within communities is a central issue in microbial ecology, and our ability to engineer and control microbial communities depends, to a large extent, on our knowledge of these interactions. This review highlights the recent advances regarding molecular characterization of microbe-microbe interactions that modulate community structure, activity, and stability, and aims to illustrate how these findings have helped us reach an engineering-level understanding of microbial communities in relation to both human health and industrial biotechnology.
微生物活动通常受到混合物种群落中共存微生物之间相互作用的影响。剖析群落内物种相互作用的分子机制是微生物生态学的核心问题，而我们对微生物群落进行工程设计和控制的能力在很大程度上取决于我们对这些相互作用的了解。本综述重点介绍了在调节群落结构、活性和稳定性的微生物-微生物相互作用分子表征方面的最新进展，旨在说明这些发现如何帮助我们在人类健康和工业生物技术方面达到对微生物群落的工程水平理解。
