Sevinçer Güzin M, Allison Kelly C
Istanbul Gelisim University, Department of Psychology, Istanbul, Turkey.
Perelman School of Medicine at the University of Pennsylvania Center for Weight and Eating Disorders (Suite 3027) and Stunkard Weight Management Program (Mezzanine), 3535 Market Street, Philadelphia, PA 19104-3309, United States.
Eat Behav. 2016 Aug;22:83-86. doi: 10.1016/j.eatbeh.2016.03.022. Epub 2016 Apr 6.
Night eating syndrome (NES) represents a circadian delay in the pattern of eating. As there are genetic links for other eating- and circadian-based disorders, it is likely that there is a genetic basis for NES as well. We present a family case study of three identified patients and their extensive family history of NES and co-morbid mood disorders. This case report suggested that NES may have a heritable feature, particularly nocturnal ingestions. Of the seven identified cases, four had co-morbid mood disorders, and all descended from a couple with bipolar disorder and delusional disorder. More work is needed to understand the extent of genetic influence on NES, and the relationship between NES and other psychiatric disorders.
夜间进食综合征(NES)表现为进食模式中的昼夜节律延迟。由于其他基于进食和昼夜节律的疾病存在遗传联系,夜间进食综合征很可能也有遗传基础。我们展示了一个家族病例研究,涉及三名确诊患者及其夜间进食综合征和共病情绪障碍的详尽家族史。该病例报告表明,夜间进食综合征可能具有遗传特征,尤其是夜间进食。在七例确诊病例中,四例患有共病情绪障碍,且均来自一对患有双相情感障碍和妄想障碍的夫妇。需要开展更多研究以了解遗传因素对夜间进食综合征的影响程度,以及夜间进食综合征与其他精神疾病之间的关系。