慢性游走性红斑患者的皮肤小/中等大小CD4+多形性T细胞淋巴瘤样结节
Cutaneous Small/Medium CD4+ Pleomorphic T-Cell Lymphoma-Like Nodule in a Patient With Erythema Chronicum Migrans.
作者信息
Celebi Cherukuri Nil, Roth Christine G, Aggarwal Nidhi, Ho Jonhan, Gehris Robin, Akilov Oleg E
机构信息
*Department of Dermatology, University of Pittsburgh, Pittsburgh, PA; †Division of Hematopathology, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA; ‡Division of Molecular and Genomic Pathology, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA; and §Pediatric Dermatology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA.
出版信息
Am J Dermatopathol. 2016 Jun;38(6):448-52. doi: 10.1097/DAD.0000000000000596.
CD4+ small/medium pleomorphic T-cell lymphoma is a relatively rare subtype of cutaneous lymphoproliferative disorder with an indolent clinical behavior. The place of this condition among lymphomas is debatable. The authors describe a rare case of the direct association of CD4 small/medium pleomorphic T-cell lymphoma-like solitary nodule with Borrelia burgdorferi infection in a 5-year-old boy, discuss the reactive nature of this condition, and emphasize the importance of clinicopathological correlation.
CD4+小/中等大小多形性T细胞淋巴瘤是皮肤淋巴增生性疾病中一种相对罕见的亚型，临床行为惰性。这种疾病在淋巴瘤中的地位存在争议。作者描述了一例5岁男孩中CD4小/中等大小多形性T细胞淋巴瘤样孤立结节与伯氏疏螺旋体感染直接相关的罕见病例，讨论了这种情况的反应性本质，并强调了临床病理相关性的重要性。
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