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创伤性脑损伤患者的酒精摄入与死亡率降低

Alcohol Intake and Reduced Mortality in Patients with Traumatic Brain Injury.

作者信息

Cho Jin Seong, Shin Sang Do, Lee Eui Jun, Song Kyoung Jun, Noh Hyun, Kim Yu Jin, Lee Seung Chul, Park Ju Ok, Kim Seong Chun, Hwang Seung-Sik

机构信息

Emergency Medicine, Gil Medical Center, Gachon University, Incheon, Korea.

Emergency Medicine, Seoul National University Hospital, Seoul, Korea.

出版信息

Alcohol Clin Exp Res. 2016 Jun;40(6):1290-4. doi: 10.1111/acer.13065. Epub 2016 Apr 21.

Abstract

BACKGROUND

The purpose of our study was to determine whether alcohol intake influences short-term mortality in patients with traumatic brain injury (TBI), using a comprehensive trauma database.

METHODS

We collected data from 7 emergency departments (EDs) between June 1, 2008 and May 31, 2010, using the same data form. Cases were included if they met the following criteria: (i) older than 15 and (ii) injuries including TBI. Demographics and outcomes were compared between patients with and without alcohol intake. We present the risk of mortality using hazard ratios and 95% confidence intervals.

RESULTS

A total of 76,596 trauma patients visited the EDs during the study period; 12,980 patients were older than 15 and had TBI. There were 4,009 (30.9%) patients in the alcohol-intake group, of whom 3,306 (82.5%) patients were male, 1,450 (36.2%) patients were moved by ambulance, and 1,218 (30.4%) patients' injuries were intentional. The most frequent injury mechanism was falling down with alcohol intake and blunt injury without alcohol intake. Mortality rate was 1.0% with alcohol intake and 2.0% without alcohol intake. After adjusting for all factors related to mortality, the hazard ratio of mortality was 0.72 in the alcohol-intake group.

CONCLUSIONS

Mortality rate due to TBI in the alcohol-intake group appears to be lower compared to that in the no-alcohol-intake group after adjusting for main confounding variables.

摘要

背景

我们研究的目的是利用一个综合创伤数据库来确定饮酒是否会影响创伤性脑损伤(TBI)患者的短期死亡率。

方法

我们使用相同的数据表格,收集了2008年6月1日至2010年5月31日期间7个急诊科的数据。符合以下标准的病例纳入研究:(i)年龄大于15岁;(ii)损伤包括TBI。比较了饮酒和未饮酒患者的人口统计学特征和结局。我们使用风险比和95%置信区间来呈现死亡风险。

结果

在研究期间,共有76,596名创伤患者前往急诊科就诊;12,980名患者年龄大于15岁且患有TBI。饮酒组有4,009名(30.9%)患者,其中3,306名(82.5%)为男性,1,450名(36.2%)患者由救护车转运,1,218名(30.4%)患者的损伤为故意伤害。最常见的损伤机制是饮酒后摔倒和未饮酒时钝器伤。饮酒组的死亡率为1.0%,未饮酒组为2.0%。在对所有与死亡率相关的因素进行调整后,饮酒组的死亡风险比为0.72。

结论

在调整主要混杂变量后,饮酒组因TBI导致的死亡率似乎低于未饮酒组。

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