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特定语言障碍中的家族聚集性。

Familial aggregation in specific language impairment.

作者信息

Tallal P, Ross R, Curtiss S

机构信息

Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ.

出版信息

J Speech Hear Disord. 1989 May;54(2):167-73. doi: 10.1044/jshd.5402.167.

Abstract

Self-report data from the families of children participating in the San Diego Longitudinal Study of specific developmental language impairment were used to assess familial aggregation in the disorder. Families of impaired children reported higher rates of affected first-degree relatives than did families of matched controls. Significantly higher incidence of maternal and paternal childhood language and/or learning disabilities, as well as sibling disability rates, were reported. The extent to which familial aggregation reflects genetic or environmental influences in specific language disorders remains to be determined.

摘要

来自参与圣地亚哥特定发育性语言障碍纵向研究的儿童家庭的自我报告数据,被用于评估该疾病中的家族聚集性。与匹配对照组的家庭相比,受损儿童的家庭报告的一级亲属受影响率更高。报告显示,母亲和父亲童年时期的语言和/或学习障碍发生率以及兄弟姐妹的残疾率显著更高。家族聚集性在多大程度上反映了特定语言障碍中的遗传或环境影响仍有待确定。

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