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硬化性肠系膜脂膜炎合并低级别滤泡性淋巴瘤罕见病例。

Rare case of sclerosing mesenteritis and low grade follicular lymphoma.

作者信息

Shah Seema, Mahy Gillian, Roche Enrico

机构信息

Seema Shah, Gillian Mahy, Enrico Roche, the Townsville Hospital, Douglas, Townsville, QLD 4810, Australia.

出版信息

World J Clin Cases. 2016 Apr 16;4(4):108-11. doi: 10.12998/wjcc.v4.i4.108.

DOI:10.12998/wjcc.v4.i4.108
PMID:27099861
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4832116/
Abstract

An unusual case of long standing sclerosing mesenteritis; initially presented with recurrent abdominal pain and a mesenteric mass with surrounding fat oedema and stranding with a pseudocapsule and fat ring sign were clearly visualised on the initial computed tomography scan. Laparotomy showed diffuse thickening at the root of the mesentery and histology from this specimen revealed fat necrosis and reactive lymphoid tissue consistent with sclerosing mesenteritis. Initial treatment with steroids and tamoxifen relieved the symptoms and the mass. He was maintained on tamoxifen. Three years later he developed a recurrence of his symptoms and abdominal mass that responded to a course of steroids. Two years following this, he developed a follicular Hodgkin's lymphoma.

摘要

一例罕见的长期硬化性肠系膜炎症;最初表现为反复腹痛,肠系膜肿块伴周围脂肪水肿及条索状改变,在初次计算机断层扫描中清晰可见假包膜和脂肪环征。剖腹探查显示肠系膜根部弥漫性增厚,该标本的组织学检查显示脂肪坏死和反应性淋巴组织,符合硬化性肠系膜炎症。最初使用类固醇和他莫昔芬治疗可缓解症状和肿块。他一直服用他莫昔芬。三年后,他的症状和腹部肿块复发,对一个疗程的类固醇治疗有反应。此后两年,他患上了滤泡性霍奇金淋巴瘤。

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本文引用的文献

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An unusual presentation of sclerosing mesenteritis as pneumoperitoneum: case report with a review of the literature.以气腹形式表现的硬化性腹膜炎:病例报告及文献复习
World J Gastroenterol. 2009 Jan 7;15(1):117-20. doi: 10.3748/wjg.15.117.
2
A clinical case study: sclerosing mesenteritis presenting as chylous ascites.一个临床病例研究:表现为乳糜性腹水的硬化性肠系膜炎症。
Medscape J Med. 2008 Feb 7;10(2):30.
3
Sclerosing mesenteritis: clinical features, treatment, and outcome in ninety-two patients.硬化性肠系膜脂膜炎:92例患者的临床特征、治疗及预后
Clin Gastroenterol Hepatol. 2007 May;5(5):589-96; quiz 523-4. doi: 10.1016/j.cgh.2007.02.032.
4
Successful management of symptoms of steroid-dependent mesenteric panniculitis with colchicine.
Dig Dis Sci. 2006 Jul;51(7):1245-9. doi: 10.1007/s10620-006-8044-5.
5
Mesenteric panniculitis in oncologic patients: PET-CT findings.肿瘤患者的肠系膜脂膜炎:PET-CT表现
Br J Radiol. 2006 Jan;79(937):37-43. doi: 10.1259/bjr/29320216.
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CT findings in sclerosing mesenteritis (panniculitis): spectrum of disease.硬化性脂膜炎(脂膜炎)的CT表现:疾病谱
Radiographics. 2003 Nov-Dec;23(6):1561-7. doi: 10.1148/rg.1103035010.
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A pilot study of thalidomide for patients with symptomatic mesenteric panniculitis.
Aliment Pharmacol Ther. 2002 Dec;16(12):2115-22. doi: 10.1046/j.1365-2036.2002.01383.x.
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CT evaluation of mesenteric panniculitis: prevalence and associated diseases.肠系膜脂膜炎的CT评估:患病率及相关疾病
AJR Am J Roentgenol. 2000 Feb;174(2):427-31. doi: 10.2214/ajr.174.2.1740427.