Suppr超能文献

[在人工循环和心脏跳动状态下对冠状动脉搭桥术的血流动力学评估]

[Flowmetric assessment of coronary bypass grafts in the conditions of artificial circulation and on the beating heart].

作者信息

Bazylev V V, Nemchenko E V, Karnakhin V A, Pavlov A A, Mikulyak A I

机构信息

Federal Centre of Cardiovascular Surgery under the RF Public Health Ministry, Penza, Russia.

出版信息

Angiol Sosud Khir. 2016;22(1):67-72.

Abstract

Advantages and shortcomings of aortocoronary bypass grafting on the beating heart and in the conditions of artificial circulation (AC) have long been discussed. The data on patency of bypass grafts in the remote period are indicative of comparable results of operations with and without AC or advantages of using AC. In order to determine benefits of each method it is necessary to reveal intraoperative predictors of bypass grafts occlusion in the remote period. We analyzed the results of ultrasound flowmetry of the blood flow through the left internal thoracic artery during bypass grafting of the anterior descending artery with the use of AC and on the beating heart. A retrospective study included a total of 352 patients subdivided into 2 groups: Group One was composed of 120 patients undergoing surgery in the conditions of AC and Group Two comprised 232 patients subjected to similar operations on the beating heart. Blood flow was measured with the help of flowmeter VeryQ MediStim® after termination of AC and inactivation of heparin by protamine, with systolic pressure of 100-110 mm Hg. There were no statistically significant differences between the groups by the diameter and degree of stenosis of the anterior descending artery, diameter of the left internal thoracic artery. The mean volumetric blood flow velocity (Qmean) along the shunts in Group One was higher (p=0.01). No statistically significant differences by the pulsatility index (PI) between the groups were revealed (p=0.2). A conclusion was drawn that coronary bypass grafting of the anterior descending artery by the left internal thoracic artery in the conditions of artificial circulation made it possible to achieve higher volumetric velocity of blood flow through the conduit as compared with operations on the beating heart, with similar resistance index. The immediate results of the operations with the use of the both techniques did not differ.

摘要

关于在心脏跳动状态下和人工循环(AC)条件下进行主动脉冠状动脉旁路移植术的优缺点,长期以来一直存在讨论。远期旁路移植物通畅性的数据表明,有或没有AC的手术结果相当,或者使用AC有优势。为了确定每种方法的益处,有必要揭示远期旁路移植物闭塞的术中预测因素。我们分析了在使用AC和在心脏跳动状态下进行前降支动脉旁路移植术时,通过左内乳动脉的血流超声流量计测量结果。一项回顾性研究共纳入352例患者,分为2组:第一组由120例在AC条件下接受手术的患者组成,第二组包括232例在心脏跳动状态下接受类似手术的患者。在AC结束且鱼精蛋白使肝素失活后,使用VeryQ MediStim®流量计在收缩压为100 - 110 mmHg时测量血流。两组在前降支动脉的直径和狭窄程度、左内乳动脉的直径方面无统计学显著差异。第一组分流处的平均体积血流速度(Qmean)更高(p = 0.01)。两组之间的搏动指数(PI)无统计学显著差异(p = 0.2)。得出的结论是,与在心脏跳动状态下进行的手术相比,在人工循环条件下通过左内乳动脉对前降支动脉进行冠状动脉旁路移植术能够实现更高的通过管道的体积血流速度,阻力指数相似。两种技术手术的近期结果无差异。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验