Strohmaier W L, Bichler K H
Med Klin (Munich). 1989 Feb 15;84(2):86-9.
In a prospective study 60 patients suffering from histologically confirmed renal cell carcinoma were examined on paraneoplastic alterations. The following parameters were determined: Stauffer-syndrome (BSG, total protein with serum electrophoresis, alcaline phosphatase, gamma-GT, Quick values), total and ionized calcium, parathormone, calcitonin, hemoglobin, thrombocytes, LDH, IgE and arterial blood pressure. Compared to the findings obtained by other authors, we saw paraneoplastic syndromes only rarely. There was no correlation found to the stage of the tumor or to prognosis. In only four out of 60 patients paraneoplastic led to the diagnosis "renal carcinoma". With the exception of BGS, which was raised in 75% of the patients, paraneoplastic parameters are not suitable for the screening or the early diagnosis of renal carcinomas.
在一项前瞻性研究中，对60例经组织学确诊的肾细胞癌患者进行了副肿瘤改变检查。测定了以下参数：斯陶弗综合征（BSG、血清电泳总蛋白、碱性磷酸酶、γ-GT、奎克值）、总钙和离子钙、甲状旁腺激素、降钙素、血红蛋白、血小板、乳酸脱氢酶、免疫球蛋白E和动脉血压。与其他作者的研究结果相比，我们很少见到副肿瘤综合征。未发现其与肿瘤分期或预后相关。60例患者中只有4例因副肿瘤表现而确诊为“肾癌”。除75%的患者BSG升高外，副肿瘤参数不适用于肾癌的筛查或早期诊断。
