一名患有局灶性癫痫发作且意识受损的16岁女孩：与弥漫性致痫网络相关的不同无创数据。
A 16-year-old girl with focal seizures and impaired awareness: divergent non-invasive data related to a diffuse epileptogenic network.
作者信息
Russo Angelo, Jayakar Prasanna, Miller Ian, Bhatia Sanjiv, Duchowny Michael
机构信息
IRCCS, Institute of Neurological Sciences of Bologna, Child Neurology Unit, Bologna, Italy.
Department of Neurology and Comprehensive Epilepsy Program, Brain Institute, Nicklaus Children's Hospital, Miami, Florida.
出版信息
Epileptic Disord. 2016 Jun 1;18(2):187-94. doi: 10.1684/epd.2016.0820.
We describe a patient with medically refractory focal epilepsy who presented with divergent non-invasive data, with MRI revealing hippocampal sclerosis and EEG indicating involvement of the occipital lobe. A localized corticectomy over the occipital convexity was performed based on intracranial EEG recording. The patient was seizure-free after four years of follow-up. Electroclinical hypotheses and challenges of defining the epileptogenic network are discussed.
我们描述了一名患有药物难治性局灶性癫痫的患者，其无创检查数据存在分歧，磁共振成像（MRI）显示海马硬化，脑电图（EEG）表明枕叶受累。基于颅内脑电图记录，在枕叶凸面进行了局部皮质切除术。经过四年的随访，患者无癫痫发作。本文还讨论了电临床假说以及定义致痫网络所面临的挑战。
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