Funk R, Rohen J W
Department of Anatomy, University of Erlangen, FRG.
Ophthalmic Res. 1989;21(1):8-17. doi: 10.1159/000266761.
Intraocular microendoscopy is introduced as a new method which allows a direct in vivo observation of the microvasculature of the eye. Using video equipment, a quantitative evaluation of changes in vessel diameters, e.g. after administration of vasoactive agents, and an estimation of blood oxygenation are possible. Experimental studies with fluorescent dyes can also be performed using special filters. In albino rabbits, no apparent vascular disturbances were observed under certain experimental conditions. Touching a ciliary process with the tip of the endoscope immediately resulted in a vasodilation and stoppage of blood flow, surprisingly in the affected area only. After epinephrine, the locally traumatized ciliary processes remained unchanged while the vessels of the neighboring ciliary processes constricted intensely. After reduction of the intraocular pressure the major ciliary processes began to swell. A leakage of fluorescein-dextran was only found in the iridial ciliary processes.
眼内显微内镜作为一种新方法被引入,它能够在体内直接观察眼睛的微血管系统。使用视频设备,可以对血管直径的变化进行定量评估,例如在使用血管活性药物后,还能够估计血液氧合情况。使用特殊滤光片也可以进行荧光染料的实验研究。在白化兔中,在某些实验条件下未观察到明显的血管紊乱。用内镜尖端触碰睫状突会立即导致血管扩张和血流停止,令人惊讶的是仅在受影响区域出现这种情况。使用肾上腺素后,局部受创伤的睫状突保持不变,而相邻睫状突的血管则强烈收缩。降低眼压后,主要的睫状突开始肿胀。仅在虹膜睫状突中发现了荧光素 - 葡聚糖的渗漏。