单相抑郁症患者褪黑素的光抑制作用

Light suppression of melatonin in unipolar depressed patients.

作者信息

Cummings M A, Berga S L, Cummings K L, Kripke D F, Haviland M G, Golshan S, Gillin J C

机构信息

Psychiatry Service, Jerry L. Pettis Memorial VA Medical Center, Loma Linda, CA 92357.

出版信息

Psychiatry Res. 1989 Mar;27(3):351-5. doi: 10.1016/0165-1781(89)90149-2.

DOI:10.1016/0165-1781(89)90149-2

PMID:2710871

Abstract

The effects of nocturnal light (500 lux) exposure on plasma melatonin were studied in seven men suffering from unipolar depression and in seven healthy men. Both groups showed significant declines in plasma melatonin concentrations during 1 hour's light exposure. Differential group declines were not detected.

摘要

研究了夜间暴露于500勒克斯光照下对7名单相抑郁症男性患者和7名健康男性血浆褪黑素的影响。两组在暴露于光照1小时期间血浆褪黑素浓度均显著下降。未检测到两组之间的差异下降。