Mazzeo R S, Pitrone F, Costantino G, Pellegrino E, Pustorino S, Ghivehcimotlagh A, Mileto G
Recenti Prog Med. 1989 Feb;80(2):76-7.
The authors report a case of severe granulocytopenia without increased susceptibility to infections in a patient with IRC (chronic renal failure) on hemofiltration treatment. The possible pathogenetic mechanisms are examined. The phenomenon is probably due to an altered compartmentation of neutrophils; the temporariness and the quick correction of the granulocytopenia explain the lack of clinical manifestations.
作者报告了1例接受血液滤过治疗的慢性肾功能衰竭(IRC)患者出现严重粒细胞减少但感染易感性未增加的病例。对可能的发病机制进行了研究。这种现象可能是由于中性粒细胞的分布改变所致;粒细胞减少的暂时性和快速纠正解释了临床表现的缺乏。