Czarnecki C M
Department of Veterinary Biology, College of Veterinary Medicine, University of Minnesota, St. Paul 55108.
Res Commun Chem Pathol Pharmacol. 1989 Feb;63(2):293-6.
Toxic effects of 1,2-diethylhydrazine, a putative furazolidone metabolite, were determined in turkey poults 2 to 5 weeks of age. The drug was administered either in the drinking water or by gastric intubation. Toxic effects included depression of growth, decreased feed intake, and increased feed conversion. There was no evidence of an induced cardiomyopathy. These findings indicate that the etiology of furazolidone toxicity involves more than one mechanism.
1,2 - 二乙基肼是一种假定的呋喃唑酮代谢产物,对2至5周龄的小火鸡的毒性作用进行了测定。该药物通过饮水或胃插管给药。毒性作用包括生长抑制、采食量减少和饲料转化率提高。没有证据表明诱发了心肌病。这些发现表明,呋喃唑酮毒性的病因涉及多种机制。