A backup cytokinesis pathway in Trypanosoma brucei.
作者信息
Zhou Qing, Li Ziyin
机构信息
a Department of Microbiology and Molecular Genetics , McGovern Medical School, University of Texas Health Science Center at Houston , TX , USA.
出版信息
Cell Cycle. 2016 Sep 16;15(18):2379-80. doi: 10.1080/15384101.2016.1181882. Epub 2016 Apr 25.
Abstract
摘要
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A backup cytokinesis pathway in Trypanosoma brucei.布氏锥虫中的一条备用胞质分裂途径。
Cell Cycle. 2016 Sep 16;15(18):2379-80. doi: 10.1080/15384101.2016.1181882. Epub 2016 Apr 25.
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The trypanosome-specific proteins FPRC and CIF4 regulate cytokinesis initiation by recruiting CIF1 to the cytokinesis initiation site.锥虫特异性蛋白 FPRC 和 CIF4 通过将 CIF1 募集到胞质分裂起始位点来调节胞质分裂的起始。
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Structural Domains of CIF3 Required for Interaction with Cytokinesis Regulatory Proteins and for Cytokinesis Initiation in Trypanosoma brucei.卷曲螺旋结构域蛋白 3 与细胞分裂调控蛋白相互作用及在布氏锥虫细胞分裂起始中的结构域。
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Functional Analyses of Cytokinesis Regulators in Bloodstream Stage Trypanosoma brucei Parasites Identify Functions and Regulations Specific to the Life Cycle Stage.血液阶段布氏锥虫寄生虫细胞分裂调控因子的功能分析，确定了特定生命周期阶段的功能和调控。
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The CIF1 protein is a master orchestrator of trypanosome cytokinesis that recruits several cytokinesis regulators to the cytokinesis initiation site.CIF1 蛋白是原生动物细胞分裂的总协调者，它将几个细胞分裂调节因子募集到细胞分裂起始位点。
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引用本文的文献
1
The trypanosome-specific proteins FPRC and CIF4 regulate cytokinesis initiation by recruiting CIF1 to the cytokinesis initiation site.锥虫特异性蛋白 FPRC 和 CIF4 通过将 CIF1 募集到胞质分裂起始位点来调节胞质分裂的起始。
J Biol Chem. 2019 Nov 8;294(45):16672-16683. doi: 10.1074/jbc.RA119.010538. Epub 2019 Sep 20.
2
Functional Analyses of Cytokinesis Regulators in Bloodstream Stage Trypanosoma brucei Parasites Identify Functions and Regulations Specific to the Life Cycle Stage.血液阶段布氏锥虫寄生虫细胞分裂调控因子的功能分析，确定了特定生命周期阶段的功能和调控。
mSphere. 2019 May 1;4(3):e00199-19. doi: 10.1128/mSphere.00199-19.
3
Overexpression of Trypanosoma cruzi High Mobility Group B protein (TcHMGB) alters the nuclear structure, impairs cytokinesis and reduces the parasite infectivity.克氏锥虫高迁移率族 B 蛋白（TcHMGB）的过表达改变核结构，损害胞质分裂，并降低寄生虫感染力。
Sci Rep. 2019 Jan 17;9(1):192. doi: 10.1038/s41598-018-36718-0.
本文引用的文献
1
Two distinct cytokinesis pathways drive trypanosome cell division initiation from opposite cell ends.两条不同的胞质分裂途径从相对的细胞末端驱动锥虫细胞分裂起始。
Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3287-92. doi: 10.1073/pnas.1601596113. Epub 2016 Feb 29.
2
Cytokinesis in Trypanosoma brucei differs between bloodstream and tsetse trypomastigote forms: implications for microtubule-based morphogenesis and mutant analysis.布氏锥虫的胞质分裂在血液和采采蝇循环型锥虫间存在差异：对微管基础形态发生和突变体分析的影响。
Mol Microbiol. 2013 Dec;90(6):1339-55. doi: 10.1111/mmi.12436. Epub 2013 Nov 15.
3
The Aurora Kinase in Trypanosoma brucei plays distinctive roles in metaphase-anaphase transition and cytokinetic initiation.布氏锥虫中的极光激酶在中期-后期转变和细胞分裂起始过程中发挥着独特作用。
PLoS Pathog. 2009 Sep;5(9):e1000575. doi: 10.1371/journal.ppat.1000575. Epub 2009 Sep 11.
4
Positioning cytokinesis.定位胞质分裂
Genes Dev. 2009 Mar 15;23(6):660-74. doi: 10.1101/gad.1772009.
5
An aurora kinase homologue is involved in regulating both mitosis and cytokinesis in Trypanosoma brucei.一种极光激酶同源物参与调控布氏锥虫的有丝分裂和胞质分裂。
J Biol Chem. 2006 Apr 7;281(14):9677-87. doi: 10.1074/jbc.M511504200. Epub 2006 Jan 24.
6
Dissociation of cytokinesis initiation from mitotic control in a eukaryote.真核生物中胞质分裂起始与有丝分裂控制的解离。
Eukaryot Cell. 2006 Jan;5(1):92-102. doi: 10.1128/EC.5.1.92-102.2006.
7
A differential role for actin during the life cycle of Trypanosoma brucei.肌动蛋白在布氏锥虫生命周期中的不同作用。
EMBO J. 2004 Feb 25;23(4):780-9. doi: 10.1038/sj.emboj.7600094. Epub 2004 Feb 12.
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