Worrell Stephanie, DeMeester Steven R
Department of Surgery, Keck School of Medicine, The University of Southern California, Los Angeles, CA, USA.
Department of Surgery, Keck School of Medicine, The University of Southern California, Los Angeles, CA, USA.
Thorac Surg Clin. 2016 May;26(2):173-6. doi: 10.1016/j.thorsurg.2015.12.005. Epub 2016 Feb 10.
Endoscopic resection and ablation have become the preferred therapy for most patients with high-grade dysplasia or superficial esophageal cancer. Endoscopic therapy offers esophageal preservation with similar oncologic outcomes and significantly fewer complications compared with the alternative of esopahgectomy. The goal of endotherapy is eradication of all the premalignant intestinal metaplasia to minimize the risk for metachronous cancer development. Once accomplished, careful follow-up is necessary to address recurrent intestinal metaplasia or dysplasia and prevent long-term failure of an endoscopic approach in these patients.
内镜切除和消融已成为大多数高级别异型增生或浅表食管癌患者的首选治疗方法。与食管切除术相比，内镜治疗可保留食管，肿瘤学结局相似，并发症明显更少。内镜治疗的目标是根除所有癌前肠化生，以降低异时性癌症发生的风险。一旦完成治疗，必须进行仔细的随访，以处理复发性肠化生或异型增生，并防止这些患者内镜治疗的长期失败。
