Kraemer Markus, Lee Sie-In, Ayzenberg Ilya, Schwitalla Jan Claudius, Diehl Rolf R, Berlit Peter, Bosche Bert, Katsarava Zaza, Obermann Mark
1 Department of Neurology, Alfried-Krupp-Hospital Essen, Germany.
2 Department of Neurology, St. Josef Hospital, Ruhr University of Bochum, Bochum, Germany.
Cephalalgia. 2017 Apr;37(5):496-500. doi: 10.1177/0333102416643516. Epub 2016 Apr 25.
Background Headache is common in patients with Moyanoya angiopathy (MMA), but usually underestimated in its management and not well characterized. Methods A validated self-administered headache screening questionnaire and a telephone interview were used in order to investigate headache characteristics, frequency and pain intensity in a large cohort of 55 German patients with MMA. Results Thirty-seven patients (67.3%) had suffered from headache in the past year. Headache intensity was rated 3.2 ± 1.3 on a verbal rating scale from 0 to 10. Seventeen patients (47.9%) reported migraine-like headache, 10 patients (27.0%) reported tension type-like headache and 10 patients (27.0%) had a combination of both. The majority of patients with migraine-like headache ( n = 10, 58.8%) described migrainous aura. Headache frequency and intensity improved significantly after revascularization surgery; however, nine patients developed new-onset headache postoperatively. Conclusion Headache is very common in MMA, often with a migraine-like phenotype. Tension type-like headache was also found in 27% of patients, which is a new finding that has not been reported before.
烟雾病（MMA）患者中头痛很常见，但在其治疗中通常被低估，且特征描述不充分。方法：使用经过验证的头痛筛查问卷进行自我管理，并进行电话访谈，以调查55名德国MMA患者的大型队列中的头痛特征、频率和疼痛强度。结果：37名患者（67.3%）在过去一年中患有头痛。头痛强度在0至10的言语评定量表上评分为3.2±1.3。17名患者（47.9%）报告有偏头痛样头痛，10名患者（27.0%）报告有紧张型头痛，10名患者（27.0%）两者皆有。大多数偏头痛样头痛患者（n = 10，58.8%）描述有偏头痛先兆。血管重建手术后头痛频率和强度显著改善；然而，9名患者术后出现新发头痛。结论：头痛在MMA中非常常见，通常具有偏头痛样表型。27%的患者也发现有紧张型头痛，这是以前未报道过的新发现。
