Jou J M, Pastor C, Labal F, Jou C, Vives Corrons J L
Sangre (Barc). 1989 Feb;34(1):14-23.
The External Quality Control Programme in Haematology (EQCP-H) comprises a monthly remittance of two whole-blood control samples for evaluating red cell count (RBC), white cell count (WBC), platelet count (PC), haematocrit (HT), haemoglobin rate (HB) and red cell indices (MCV, MHC, MCHC), as well as lyophilized plasma for prothrombin time (PT), partial thromboplastin time (PTT) and fibrinogen (F) determination. The participant laboratories were classified for each determination in accordance with the methods used. The evaluation was made on the basis of 1986 data, the number of participants being 230, from Public Health (54%) and private 46%) laboratories. A mean (means) or target value, along with the standard deviation (SD), was obtained for the results received in the Organising Centre for each parameter. In order to find deviation of individual results with respect to means, a deviation index (DI) was calculated with regard to the whole group and to those laboratories using the same methods. The graphic evaluation of the results was plotted on a Youden diagram. The active participation was 58.3 +/- 5.7%, ranging from 33% (PC) to 74% (RBC, HB, HT and MCV). Upon evaluating the whole programme, stress was laid on the global variation coefficient (VC%) attained for each parameter and those pertaining to the analytical systems employed, grouped in accordance with the methodological principles. Global VC% ranged between 3.6% (HB) and 31.9% (PTT), and the values corresponding to the analytical procedure used were below 4% for RBC, HB, MCV and MCHC in automatic systems and also for HB and MCV in semiautomatic systems. Although the working period of EQPC-H is too short to draw definitive conclusions on the improvement it may induce in the methodological quality, the high VC% values found for WBC, PC and manual determination of HB, along with the unacceptable values for PT, PTT and F, should be stressed.
血液学外部质量控制计划（EQCP-H）包括每月寄送两份全血对照样本，用于评估红细胞计数（RBC）、白细胞计数（WBC）、血小板计数（PC）、血细胞比容（HT）、血红蛋白率（HB）和红细胞指数（MCV、MHC、MCHC），以及用于凝血酶原时间（PT）、部分凝血活酶时间（PTT）和纤维蛋白原（F）测定的冻干血浆。参与实验室根据所使用的方法进行分类测定。评估基于1986年的数据，参与者有230个，来自公共卫生实验室（54%）和私人实验室（46%）。为组织中心收到的每个参数的结果获取了均值（平均数）或目标值以及标准差（SD）。为了找出各个结果相对于均值的偏差，针对整个组以及使用相同方法的实验室计算了偏差指数（DI）。结果的图形评估绘制在尤登图上。积极参与率为58.3±5.7%，范围从33%（PC）到74%（RBC、HB、HT和MCV）。在评估整个计划时，重点关注了每个参数以及与所采用分析系统相关的全局变异系数（VC%），这些系统根据方法学原理进行了分组。全局VC%在3.6%（HB）至31.9%（PTT）之间，自动系统中红细胞、血红蛋白、平均红细胞体积和平均红细胞血红蛋白浓度以及半自动系统中的血红蛋白和平均红细胞体积所对应的分析程序的值低于4%。尽管EQPC-H的运行时间太短，无法就其可能带来的方法学质量改善得出明确结论，但应强调白细胞、血小板以及血红蛋白手工测定的高VC%值，以及凝血酶原时间、部分凝血活酶时间和纤维蛋白原的不可接受值。
