Catterall M
MRC Cyclotron Unit, Hammersmith Hospital, London, UK.
Strahlenther Onkol. 1989 Apr;165(4):298-301.
Since the Hammersmith cyclotron was removed, the earlier therapy results have been extensively re-examined. The overall experiences can be summarized as follows: 1. A total neutron dose of 1560 cGy given in twelve equally spaced fractions over 20 days seems to be the optimum. Neutrons, therefore, provide a treatment option with great advantage with respect to patient management. 2. Rapid tumour regression is an important often ignored effect, leading to a quick relief of pain and other serious symptoms in the patient. 3. Due to the high incidence of complete regression complicated surgery can be avoided in many cases. Tissue deficits can be often covered by modern methods of surgery repair. 4. Local control rates are as high as 60 to 80% of the advanced tumours. They improve the quality of life and reduce the cost of continuing patients' care.
自从哈默史密斯回旋加速器被移除后，早期的治疗结果得到了广泛的重新审视。总体经验可总结如下：1. 在20天内分12等份给予1560厘戈瑞的总中子剂量似乎是最佳的。因此，中子在患者管理方面提供了一个具有巨大优势的治疗选择。2. 肿瘤快速消退是一个重要但常被忽视的效果，能使患者的疼痛和其他严重症状迅速缓解。3. 由于完全消退的发生率很高，在许多情况下可以避免复杂的手术。组织缺损通常可以通过现代手术修复方法来弥补。4. 晚期肿瘤的局部控制率高达60%至80%。它们提高了生活质量并降低了持续护理患者的成本。
