Djurendic-Brenesel Maja, Stojiljkovic Goran, Pilija Vladimir
Institute of Forensic Medicine, Clinical Center Vojvodina, Hajduk Veljkova 7-9, 21 000, Novi Sad, Serbia.
J Forensic Sci. 2016 May;61(3):875-878. doi: 10.1111/1556-4029.13019. Epub 2016 Jan 4.
Two cases of fatal intoxications with toluene due to glue sniffing are described. In case 1, the autopsy did not indicate cause of death, while in case 2, the cause of death was determined to possibly be due to mechanical asphyxia by drowning. As the decedents had a history of glue sniffing, toxicological analyses were performed. Using gas chromatography with flame ionization detector and gas chromatography/mass spectrometry (GC/MS) with headspace method, toluene was detected in biological samples. Toluene ranged from 3.81 to 20.97 μg/g, with the highest concentrations observed in liver and brain (13.82-20.97 μg/g) in both cases. Based upon this data, the cause of death in both cases was determined to be toluene poisoning. Toxicological investigations are extremely important and should be considered mandatory in all deaths thought to be due to volatile substance abuse, as well as all deaths that are thought to be due to poisoning in young people.
描述了两起因吸食胶水导致甲苯致命中毒的案例。在案例1中，尸检未表明死因，而在案例2中，死因被确定可能是溺水导致的机械性窒息。由于死者有吸食胶水的历史，因此进行了毒理学分析。使用带有火焰离子化检测器的气相色谱法和顶空法的气相色谱/质谱联用仪（GC/MS），在生物样本中检测到了甲苯。甲苯含量在3.81至20.97μg/g之间，在两个案例中，肝脏和大脑中的浓度最高（13.82 - 20.97μg/g）。基于这些数据，两个案例的死因均被确定为甲苯中毒。毒理学调查极其重要，对于所有被认为是由于挥发性物质滥用导致的死亡以及所有被认为是年轻人中毒导致的死亡，都应强制进行毒理学调查。
