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出院时调整抗糖尿病治疗对因低血糖就诊于急诊科的糖尿病患者30天结局的影响

[Effect of antidiabetes treatment adjustment at discharge on 30-day outcomes of patients with diabetes mellitus presenting to an emergency department with hypoglycemia].

作者信息

Cuervo Pinto R, Rodríguez Adrada E, Domínguez Bernal C, Chaparro Pardo D, Martín-Sánchez F J, González del Castillo J M

机构信息

Hospital Clínico San Carlos de Madrid.

出版信息

An Sist Sanit Navar. 2016 Apr 29;39(1):99-104. doi: 10.4321/S1137-6627/2016000100011.

DOI:10.4321/S1137-6627/2016000100011
PMID:27125618
Abstract

BACKGROUND

To determine if antidiabetes treatment adjustment at discharge from an Emergency Department(ED) is associated with 30-day outcomes in patients with diabetes mellitus presenting to the ED with hypoglycemia.

METHODS

Retrospective cohort observational study. Patients with diabetes mellitus presenting to the ED with hypoglycemia directly discharged from the ED between 2012-2014 were included. Primary outcome was a 30-day composite adverse event(mortality or revisiting).

RESULTS

A total of 203 patients were included with a mean age of 69.7 (SD 18.9), mainly type 2 diabetics.Hypoglycemia was the primary diagnosis in 162(79%) of patients and antidiabetes treatment was adjusted at discharge in 98 (48%) of cases. Non-adjustment of antidiabetes treatment at ED discharge was an independent factor associated with a 30-day adverse event (OR=2.8; CI 95%=1.34-5.93; p=0.006).

CONCLUSIONS

Non-adjustment of antidiabetes treatment at discharge in patients with diabetes mellitus presenting to the ED with hypoglycemia could be an independent factor of suffering a 30-day adverse event.

摘要

背景

确定急诊科(ED)出院时抗糖尿病治疗调整是否与因低血糖到急诊科就诊的糖尿病患者的30天预后相关。

方法

回顾性队列观察研究。纳入2012年至2014年间因低血糖到急诊科就诊且直接从急诊科出院的糖尿病患者。主要结局是30天综合不良事件(死亡或再次就诊)。

结果

共纳入203例患者,平均年龄69.7岁(标准差18.9),主要为2型糖尿病患者。162例(79%)患者的主要诊断为低血糖,98例(48%)患者在出院时调整了抗糖尿病治疗。急诊科出院时未调整抗糖尿病治疗是与30天不良事件相关的独立因素(比值比=2.8;95%置信区间=1.34 - 5.93;p = 0.006)。

结论

因低血糖到急诊科就诊的糖尿病患者出院时未调整抗糖尿病治疗可能是发生30天不良事件的独立因素。

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